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UDP-D-glucuronate + 4',5,6,7-tetrahydroxyflavone
UDP + 4',5,6,7-tetrahydroxyflavone 7-O-beta-D-glucuronate
UDP-D-glucuronate + 5,6,7-trihydroxyflavone
UDP + 5,6,7-trihydroxyflavone-7-O-beta-D-glucuronate
UDP-D-glucuronate + 5,7-dihydroxy-8-methoxyflavone
UDP + 5,7-dihydroxy-8-methoxyflavone-7-O-beta-D-glucuronate
UDP-D-glucuronate + baicalein
UDP + baicalin
UDP-glucuronate + baicalein
UDP + baicalin
-
-
-
-
?
additional information
?
-
UDP-D-glucuronate + 4',5,6,7-tetrahydroxyflavone
UDP + 4',5,6,7-tetrahydroxyflavone 7-O-beta-D-glucuronate
-
i.e. 5,6,7-trihydroxy-2-(4-hydroxyphenyl)chromen-4-one, i.e. scutellarein. The enzyme is specific to UDP-glucuronic acid as a sugar donor and flavones with substitution ortho- to the 7-OH group such as baicalein (6-OH), scutellarein (6-OH) and wogonin (8-OMe)
i.e. scutellarein 7-O-glucuronide
-
?
UDP-D-glucuronate + 4',5,6,7-tetrahydroxyflavone
UDP + 4',5,6,7-tetrahydroxyflavone 7-O-beta-D-glucuronate
-
i.e. 5,6,7-trihydroxy-2-(4-hydroxyphenyl)chromen-4-one, i.e. scutellarein. The enzyme is specific to UDP-glucuronic acid as a sugar donor and flavones with substitution ortho- to the 7-OH group such as baicalein (6-OH), scutellarein (6-OH) and wogonin (8-OMe)
i.e. scutellarein 7-O-glucuronide
-
?
UDP-D-glucuronate + 5,6,7-trihydroxyflavone
UDP + 5,6,7-trihydroxyflavone-7-O-beta-D-glucuronate
-
i.e. 5,6,7-trihydroxy-2-phenyl-4H-chromen-4-one, i.e. baicalein. The enzyme is specific to UDP-glucuronic acid as a sugar donor and flavones with substitution ortho- to the 7-OH group such as baicalein (6-OH), scutellarein (6-OH) and wogonin (8-OMe)
i.e. 5,6-dihydroxy-4-oxo-2-phenyl-4H-chromen-7-yl beta-D-glucopyranosiduronic acid, i.e. baicalein 7-O-glucuronide, i.e. 5,6-dihydroxy-4-oxo-2-phenyl-4H-chromen-7-yl beta-D-glucopyranosiduronic acid, i.e. baicalein 7-O-glucuronide. Identification and quantitation of the enzyme reaction products are carried out by reversed phase-HPLC
-
?
UDP-D-glucuronate + 5,6,7-trihydroxyflavone
UDP + 5,6,7-trihydroxyflavone-7-O-beta-D-glucuronate
-
i.e. 5,6,7-trihydroxy-2-phenyl-4H-chromen-4-one, i.e. baicalein. The enzyme is specific to UDP-glucuronic acid as a sugar donor and flavones with substitution ortho- to the 7-OH group such as baicalein (6-OH), scutellarein (6-OH) and wogonin (8-OMe)
i.e. 5,6-dihydroxy-4-oxo-2-phenyl-4H-chromen-7-yl beta-D-glucopyranosiduronic acid, i.e. baicalein 7-O-glucuronide, i.e. 5,6-dihydroxy-4-oxo-2-phenyl-4H-chromen-7-yl beta-D-glucopyranosiduronic acid, i.e. baicalein 7-O-glucuronide. Identification and quantitation of the enzyme reaction products are carried out by reversed phase-HPLC
-
?
UDP-D-glucuronate + 5,7-dihydroxy-8-methoxyflavone
UDP + 5,7-dihydroxy-8-methoxyflavone-7-O-beta-D-glucuronate
-
i.e. 5,7-dihydroxy-8-methoxy-2-phenylchromen-4-one, i.e. wogonin. The enzyme is specific to UDP-glucuronic acid as a sugar donor and flavones with substitution ortho- to the 7-OH group such as baicalein (6-OH), scutellarein (6-OH) and wogonin (8-OMe)
i.e wogonin 7-O-glucuronide
-
?
UDP-D-glucuronate + 5,7-dihydroxy-8-methoxyflavone
UDP + 5,7-dihydroxy-8-methoxyflavone-7-O-beta-D-glucuronate
-
i.e. 5,7-dihydroxy-8-methoxy-2-phenylchromen-4-one, i.e. wogonin. The enzyme is specific to UDP-glucuronic acid as a sugar donor and flavones with substitution ortho- to the 7-OH group such as baicalein (6-OH), scutellarein (6-OH) and wogonin (8-OMe)
i.e wogonin 7-O-glucuronide
-
?
UDP-D-glucuronate + baicalein
UDP + baicalin
-
-
-
?
UDP-D-glucuronate + baicalein
UDP + baicalin
-
-
-
?
additional information
?
-
-
flavonoids lacking a substitution at the position ortho- to the 7-OH (chrysin, apigenin, luteolin, quercetin, formononetin and daidzein) do not serve as substrates
-
-
?
additional information
?
-
-
flavonoids lacking a substitution at the position ortho- to the 7-OH (chrysin, apigenin, luteolin, quercetin, formononetin and daidzein) do not serve as substrates
-
-
?
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UDP-D-glucuronate + 5,6,7-trihydroxyflavone
UDP + 5,6,7-trihydroxyflavone-7-O-beta-D-glucuronate
UDP-D-glucuronate + baicalein
UDP + baicalin
UDP-glucuronate + baicalein
UDP + baicalin
-
-
-
-
?
UDP-D-glucuronate + 5,6,7-trihydroxyflavone
UDP + 5,6,7-trihydroxyflavone-7-O-beta-D-glucuronate
-
i.e. 5,6,7-trihydroxy-2-phenyl-4H-chromen-4-one, i.e. baicalein. The enzyme is specific to UDP-glucuronic acid as a sugar donor and flavones with substitution ortho- to the 7-OH group such as baicalein (6-OH), scutellarein (6-OH) and wogonin (8-OMe)
i.e. 5,6-dihydroxy-4-oxo-2-phenyl-4H-chromen-7-yl beta-D-glucopyranosiduronic acid, i.e. baicalein 7-O-glucuronide
-
?
UDP-D-glucuronate + 5,6,7-trihydroxyflavone
UDP + 5,6,7-trihydroxyflavone-7-O-beta-D-glucuronate
-
i.e. 5,6,7-trihydroxy-2-phenyl-4H-chromen-4-one, i.e. baicalein. The enzyme is specific to UDP-glucuronic acid as a sugar donor and flavones with substitution ortho- to the 7-OH group such as baicalein (6-OH), scutellarein (6-OH) and wogonin (8-OMe)
i.e. 5,6-dihydroxy-4-oxo-2-phenyl-4H-chromen-7-yl beta-D-glucopyranosiduronic acid, i.e. baicalein 7-O-glucuronide
-
?
UDP-D-glucuronate + baicalein
UDP + baicalin
-
-
-
?
UDP-D-glucuronate + baicalein
UDP + baicalin
-
-
-
?
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Nagashima, S.; Hirotani, M.; Yoshikawa, T.
Purification and characterization of UDP-glucuronate: baicalein 7-O-glucuronosyltransferase from Scutellaria baicalensis Georgi. cell suspension cultures
Phytochemistry
53
533-538
2000
Scutellaria baicalensis, Scutellaria baicalensis Georgi
brenda
Wang, W.; Chen, J.-k.; Zhou, T.-s.
CHS and UBGAT expression and baicalin accumulation in the roots of Scutellaria baicalensis Georgi during cultivation seasons
Fudan Xuebao Ziran Kexueban
45
674-678
2006
Scutellaria baicalensis
-
brenda
Yuan, Y.; Shuai, L.; Chen, S.; Huang, L.; Qin, S.; Yang, Z.
Flavonoids and antioxidative enzymes in temperature-challenged roots of Scutellaria baicalensis Georgi
Z. Naturforsch. C
67
77-85
2012
Scutellaria baicalensis (Q76MR7), Scutellaria baicalensis
brenda
Qi, S.; Cao, W.; Hua, J.; Zhang, A.; Meng, X.
H2O2 improves quality of radix scutellariae through anti-oxidant effect
Pharmacogn. Mag.
12
84-90
2016
Scutellaria baicalensis (Q76MR7), Scutellaria baicalensis, Scutellaria baicalensis Georgi (Q76MR7)
brenda