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Information on EC 2.1.1.46 - isoflavone 4'-O-methyltransferase

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EC Tree
     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.46 isoflavone 4'-O-methyltransferase
IUBMB Comments
Requires Mg2+ for activity. The enzyme catalyses the methylation of daidzein and genistein. It does not methylate naringenin, apigenin, luteolin or kaempferol.
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The enzyme appears in viruses and cellular organisms
Synonyms
isoflavone-specific 4'-o-methyltransferase, 2,7,4'-trihydroxyisoflavanone 4'-o-methyltransferase/isoflavone 4'-o-methyltransferase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
S-adenosyl-L-methionine + a 4'-hydroxyisoflavone = S-adenosyl-L-homocysteine + a 4'-methoxyisoflavone
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