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Information on EC 1.8.2.2 - thiosulfate dehydrogenase

for references in articles please use BRENDA:EC1.8.2.2

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IUBMB Comments

The enzyme catalyses the reversible formation of a sulfur-sulfur bond between the sulfane atoms of two thiosulfate molecules, yielding tetrathionate and releasing two electrons. In many bacterial species the enzyme is a diheme c-type cytochrome. In a number of organisms, including Thiomonas intermedia and Sideroxydans lithotrophicus, a second diheme cytochrome (TsdB) acts as the electron acceptor. However, some organisms, such as Allochromatium vinosum, lack TsdB. The electron acceptor in these organisms may be the high-potential iron-sulfur protein (HiPIP).

The expected taxonomic range for this enzyme is: Bacteria, Eukaryota

Synonyms
thiosulfate dehydrogenase, thiosulfate oxidase, thiosulfate-oxidizing enzyme, afe_0042, mptsdba, avtsda, tetrathionate synthase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
2 thiosulfate + 2 ferricytochrome c = tetrathionate + 2 ferrocytochrome c + 4 H+
show the reaction diagram
PATHWAY SOURCE
PATHWAYS
MetaCyc
thiosulfate oxidation I (to tetrathionate)