Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Synonyms
glutamate dehydrogenase, gdh, glud1, hgdh1, glutamic dehydrogenase, nad-gdh, l-glutamate dehydrogenase, nad-dependent glutamate dehydrogenase, nadh-gdh, glutamic acid dehydrogenase,
morePlease wait a moment until the data is sorted. This message will disappear when the data is sorted.
dehydrogenase, glutamate
-
-
-
-
glutamate dehydrogenase (NAD)
-
-
-
-
glutamate dehydrogenase 2
glutamate dehydrogenase alpha subunit
-
glutamate dehydrogenase beta subunit
-
glutamate dehydrogenase isoform 1
-
glutamate oxidoreductase
-
-
-
-
glutamic acid dehydrogenase
glutamic dehydrogenase
-
-
-
-
hGDH2-nerve-specific GDH
-
-
L-glutamate dehydrogenase
L-glutamic acid dehydrogenase
-
-
NAD(+)-dependent glutamate dehydrogenase
-
NAD(H)-dependent glutamate dehydrogenase
NAD+-dependant glutamate dehydrogenase
-
NAD+-dependent glutamate dehydrogenase
NAD+-glutamate dehydrogenase
NAD+-specific glutamate dehydrogenase
-
NAD-dependent glutamate dehydrogenase
NAD-dependent glutamic dehydrogenase
-
-
-
-
NAD-dependent L-glutamate dehydrogenase
NAD-glutamate dehydrogenase
NAD-linked glutamate dehydrogenase
-
-
-
-
NAD-linked glutamic dehydrogenase
-
-
-
-
NAD-specific glutamate dehydrogenase
-
-
-
-
NAD-specific glutamic dehydrogenase
-
-
-
-
NAD:glutamate oxidoreductase
-
-
-
-
NADH-dependent glutamate dehydrogenase
NADH-glutamate dehydrogenase
-
-
NADH-linked glutamate dehydrogenase
-
-
-
-
Surface-associated protein PGAG1
-
-
-
-
c
-
GDH
-
-
-
-
GDH isoenzyme 1
-
-
GDH, NAD-dependent
-
GDH1
-
beta subunit
GDH2
-
alpha subunit
Gdh2p
-
GDHB
-
beta subunit
GLUD1
isozyme
GluDH
-
glutamate dehydrogenase
-
-
glutamate dehydrogenase
-
glutamate dehydrogenase
-
-
glutamate dehydrogenase
-
-
glutamate dehydrogenase
-
glutamate dehydrogenase
-
glutamate dehydrogenase
-
-
glutamate dehydrogenase
-
glutamate dehydrogenase
-
-
glutamate dehydrogenase
-
-
glutamate dehydrogenase
-
-
glutamate dehydrogenase
-
-
glutamate dehydrogenase
-
-
glutamate dehydrogenase
-
glutamate dehydrogenase
-
-
glutamate dehydrogenase
-
-
glutamate dehydrogenase
-
-
glutamate dehydrogenase
-
-
glutamate dehydrogenase
-
-
glutamate dehydrogenase
-
-
glutamate dehydrogenase
-
-
glutamate dehydrogenase
-
-
glutamate dehydrogenase 2
-
glutamate dehydrogenase 2
-
-
glutamic acid dehydrogenase
-
-
-
-
glutamic acid dehydrogenase
-
-
L-glutamate dehydrogenase
-
-
-
-
L-glutamate dehydrogenase
-
-
L-glutamate dehydrogenase
-
-
-
NAD(H)-dependent glutamate dehydrogenase
-
-
NAD(H)-dependent glutamate dehydrogenase
-
NAD(H)-dependent glutamate dehydrogenase
-
-
NAD+-dependent GDH
-
-
NAD+-dependent GDHX
-
NAD+-dependent glutamate dehydrogenase
-
-
NAD+-dependent glutamate dehydrogenase
-
NAD+-dependent glutamate dehydrogenase
-
-
NAD+-dependent glutamate dehydrogenase
-
-
NAD+-dependent glutamate dehydrogenase
-
-
NAD+-glutamate dehydrogenase
-
-
NAD+-glutamate dehydrogenase
-
-
-
NAD-dependent GDH
-
NAD-dependent glutamate dehydrogenase
-
-
-
-
NAD-dependent glutamate dehydrogenase
-
NAD-dependent glutamate dehydrogenase
-
-
NAD-dependent glutamate dehydrogenase
-
NAD-dependent glutamate dehydrogenase
-
-
NAD-dependent glutamate dehydrogenase
-
NAD-dependent glutamate dehydrogenase
-
NAD-dependent glutamate dehydrogenase
-
-
NAD-dependent glutamate dehydrogenase
-
-
NAD-dependent L-glutamate dehydrogenase
-
NAD-dependent L-glutamate dehydrogenase
-
-
NAD-GDH
-
-
-
-
NAD-glutamate dehydrogenase
-
-
-
-
NAD-glutamate dehydrogenase
-
-
NAD-glutamate dehydrogenase
-
-
-
NAD-glutamate dehydrogenase
-
-
NAD-glutamate dehydrogenase
-
-
NAD-glutamate dehydrogenase
-
NAD-glutamate dehydrogenase
-
-
NAD-ylGdh2p
-
NADH-dependent GDH
-
-
NADH-dependent glutamate dehydrogenase
-
-
-
-
NADH-dependent glutamate dehydrogenase
-
-
NADH-dependent glutamate dehydrogenase
-
-
NADH-GDH
-
-
Pcal_1031
-
-
RocG
-
-
sco2999
-
t-GDH
-
-
YALI0E09603g
-
ylGDH2
-
additional information
-
cf. EC 1.4.1.3
additional information
NAD+-specific glutamate dehydrogenases belongs to the L_180 class, that is affected by the binding of a small protein, GarA
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
L-glutamate + H2O + NAD+ = 2-oxoglutarate + NH3 + NADH + H+
L-glutamate + H2O + NAD+ = 2-oxoglutarate + NH3 + NADH + H+
bi uni uni ping-pong addition sequence
-
L-glutamate + H2O + NAD+ = 2-oxoglutarate + NH3 + NADH + H+
partially random mechanism
-
L-glutamate + H2O + NAD+ = 2-oxoglutarate + NH3 + NADH + H+
fully ordered reaction mechanism
-
L-glutamate + H2O + NAD+ = 2-oxoglutarate + NH3 + NADH + H+
NAD+ binds first followed by L-glutamate
-
L-glutamate + H2O + NAD+ = 2-oxoglutarate + NH3 + NADH + H+
formation of an enzyme-NAD-oxoglutarate dead end complex
-
L-glutamate + H2O + NAD+ = 2-oxoglutarate + NH3 + NADH + H+
-
-
-
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
2-oxo-3-methylvalerate + NADPH + NH3
L-isoleucine + NADP+ + H2O
-
very low specificity of wild-type
-
-
?
2-oxo-iso-caproate + NADPH + NH3
L-norleucine + NADP+ + H2O
-
very low specificity of wild-type
-
-
?
2-oxo-iso-valerate + NADPH + NH3
L-leucine + NADP+ + H2O
-
low specificity of wild-type
-
-
?
2-oxobutanoate + NH3 + NADH + H+
L-2-aminobutanoate + H2O + NAD+
2-oxobutyrate + NADH + NH3
2-aminobutyrate + NAD+ + H2O
2-oxocaproate + NH3 + NADH + H+
L-2-aminohexanoate + H2O + NAD+
1.3% of the activity with 2-oxoglutarate
-
-
r
2-oxoglutarate + NADH + NH3
L-glutamate + NAD+ + H2O
2-oxoglutarate + NADPH + NH3
L-glutamate + NADP+ + H2O
2-oxoglutarate + NH3 + NADH
L-glutamate + H2O + NAD+
2-oxoglutarate + NH3 + NADH + H+
L-glutamate + H2O + NAD+
2-oxoglutarate + NH4+ + NADH
L-glutamate + NAD+
-
-
-
-
?
2-oxoglutarate + NH4+ + NADPH
L-glutamate + NADP+
2-oxovalerate + NH3 + NADH + H+
L-valine + H2O + NAD+
6.6% of the activity with 2-oxoglutarate
-
-
r
beta-phenylpyruvate + NADPH + NH3
L-phenylalanine + NADP+ + H2O
-
low specificity of wild-type
-
-
?
DL-norleucine + H2O + NAD+
? + NH3 + NADH + H+
-
1.6% activity compared to L-glutamate, pH 9.0
-
-
r
L-2-aminobutanoate + H2O + NAD+
2-oxobutanoate + NH3 + NADH + H+
L-alanine + H2O + NAD+
? + NH3 + NADH + H+
-
0.27% activity compared to L-glutamate, pH 9.0
-
-
r
L-alpha-aminobutyrate + H2O + NAD+
? + NH3 + NADH + H+
-
2.3% activity compared to L-glutamate, pH 9.0
-
-
r
L-glutamate + H2O + NAD(P)+
2-oxoglutarate + NH3 + NAD(P)H
L-glutamate + H2O + NAD+
2-oxoglutarate + NH3 + NADH
L-glutamate + H2O + NAD+
2-oxoglutarate + NH3 + NADH + H+
L-glutamate + H2O + NADP+
2-oxoglutarate + NH3 + NADPH
L-glutamate + H2O + NADP+
2-oxoglutarate + NH3 + NADPH + H+
-
weak reaction
-
-
?
L-glutamate + NAD+ + H2O
2-oxoglutarate + NADH + NH3
L-glutamate + NADP+ + H2O
2-oxoglutarate + NADPH + NH3
-
-
-
-
r
L-isoleucine + H2O + NAD+
2-oxo-3-methylvalerate + NH3 + NADH + H+
3.0% of the activity with L-glutamate
-
-
r
L-isoleucine + H2O + NAD+
? + NH3 + NADH + H+
-
0.95% activity compared to L-glutamate, pH 9.0
-
-
r
L-leucine + H2O + NAD+
2-oxo-iso-valerate + NH3 + NADH + H+
1.6% of the activity with L-glutamate
-
-
r
L-leucine + H2O + NAD+
2-oxoisovalerate + NH3 + NADH + H+
-
1.7% activity compared to L-glutamate, pH 9.0
-
-
r
L-methionine + H2O + NAD+
? + NH3 + NADH + H+
-
0.82% activity compared to L-glutamate, pH 9.0
-
-
r
L-norvaline + H2O + NAD+
2-oxopentanoate + NH3 + NADH
L-norvaline + H2O + NAD+
2-oxopentanoate + NH3 + NADH + H+
L-norvaline + H2O + NAD+
? + NH3 + NADH + H+
-
17% activity compared to L-glutamate, pH 9.0
-
-
r
L-serine + H2O + NAD+
3-hydroxy-2-oxopropanoate + NH3 + NADH
-
deamination at 29% the rate of L-glutamate deamination
-
-
?
L-valine + H2O + NAD+
2-oxovalerate + NH3 + NADH + H+
31% of the activity with L-glutamate
-
-
r
L-valine + H2O + NAD+
? + NH3 + NADH + H+
-
1.6% activity compared to L-glutamate, pH 9.0
-
-
r
oxaloacetate + NADPH + NH3
L-aspartate + NADP+ + H2O
p-hydroxyphenylpyruvate + NADPH + NH3
L-tyrosine + NADP+ + H2O
-
very low specificity of wild-type
-
-
?
pyruvate + NADPH + NH3
L-alanine + NADP+ + H2O
additional information
?
-
2-oxobutanoate + NH3 + NADH + H+
L-2-aminobutanoate + H2O + NAD+
2.7% of the activity with 2-oxoglutarate
-
-
r
2-oxobutanoate + NH3 + NADH + H+
L-2-aminobutanoate + H2O + NAD+
2.7% of the activity with 2-oxoglutarate
-
-
r
2-oxobutyrate + NADH + NH3
2-aminobutyrate + NAD+ + H2O
faint specificity
-
-
?
2-oxobutyrate + NADH + NH3
2-aminobutyrate + NAD+ + H2O
faint specificity
-
-
?
2-oxoglutarate + NADH + NH3
L-glutamate + NAD+ + H2O
-
1.4.1.2 glutamate dehydrogenase
top
