Methanococcus maripaludis Methanococcus maripaludis JJ Priestia megaterium Priestia megaterium DSM 509
Q977V1
No. of entries
We're sorry, but BRENDA doesn't work properly without JavaScript. Please make sure you have JavaScript enabled in your browser settings.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
IUBMB Comments The enzyme, which participates in the anaerobic (early cobalt insertion) pathway of adenosylcobalamin biosynthesis, catalyses the reduction of the double bond between C-18 and C-19 of cobalt-precorrin-6A. The enzyme from the bacterium Bacillus megaterium has no activity with NADPH. See EC 1.3.1.54 , precorrin-6A reductase, for the corresponding enzyme that participates in the aerobic cobalamin biosynthesis pathway.
Synonyms
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
CbiJ
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
cobalt-precorrin-6B + NAD+ = cobalt-precorrin-6A + NADH + H+
-
-
-
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
MetaCyc
cob(II)yrinate a,c-diamide biosynthesis I (early cobalt insertion)
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
cobalt-precorrin-6B:NAD+ oxidoreductase
The enzyme, which participates in the anaerobic (early cobalt insertion) pathway of adenosylcobalamin biosynthesis, catalyses the reduction of the double bond between C-18 and C-19 of cobalt-precorrin-6A. The enzyme from the bacterium Bacillus megaterium has no activity with NADPH. See EC 1.3.1.54, precorrin-6A reductase, for the corresponding enzyme that participates in the aerobic cobalamin biosynthesis pathway.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
cobalt-precorrin-6A + NADH + H+
cobalt-precorrin-6B + NAD+
cobalt-precorrin-6A + NADH + H+
cobalt-precorrin-6B + NAD+
-
Substrates: no activity with NADPH
?
cobalt-precorrin-6A + NADH + H+
cobalt-precorrin-6B + NAD+
-
Substrates: the enzyme catalyses a step in the anaerobic (early cobalt insertion) pathway of adenosylcobalamin biosynthesis
?
cobalt-precorrin-6A + NADH + H+
cobalt-precorrin-6B + NAD+
-
Substrates: no activity with NADPH
?
cobalt-precorrin-6A + NADH + H+
cobalt-precorrin-6B + NAD+
-
Substrates: the enzyme catalyses a step in the anaerobic (early cobalt insertion) pathway of adenosylcobalamin biosynthesis
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
cobalt-precorrin-6A + NADH + H+
cobalt-precorrin-6B + NAD+
cobalt-precorrin-6A + NADH + H+
cobalt-precorrin-6B + NAD+
-
Substrates: the enzyme catalyses a step in the anaerobic (early cobalt insertion) pathway of adenosylcobalamin biosynthesis
?
cobalt-precorrin-6A + NADH + H+
cobalt-precorrin-6B + NAD+
-
Substrates: the enzyme catalyses a step in the anaerobic (early cobalt insertion) pathway of adenosylcobalamin biosynthesis
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
NADH
-
no activity with NADPH
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
-
SwissProt
brenda
-
SwissProt
brenda
-
-
-
brenda
-
-
-
brenda
Highest Expressing Human Cell Lines
Filter by:
Cell Line Links
Gene Links
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
physiological function
gene deletion yields an auxotroph that requires either cobamide or acetate for good growth
physiological function
-
gene deletion yields an auxotroph that requires either cobamide or acetate for good growth
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
homologously overproduced enzyme
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Kim, W.; Major, T.A.; Whitman, W.B.
Role of the precorrin 6-X reductase gene in cobamide biosynthesis in Methanococcus maripaludis
Archaea
1
375-384
2005
Methanococcus maripaludis (Q977V1), Methanococcus maripaludis JJ (Q977V1)
brenda
Moore, S.; Lawrence, A.; Biedendieck, R.; Deery, E.; Frank, S.; Howard, M.; Rigby, S.; Warren, M.
Elucidation of the anaerobic pathway for the corrin component of cobalamin (vitamin B12)
Proc. Natl. Acad. Sci. USA
110
14906-14911
2013
Priestia megaterium, Priestia megaterium DSM 509
brenda
html completed
show
top
