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Information on EC 1.14.21.11 - ()-pluviatolide synthase
for references in articles please use BRENDA:EC1.14.21.11
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transferred to EC 1.14.19.72
EC Tree 1 Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.21 With NADH or NADPH as one donor, and the other dehydrogenated
1.14.21.11 ()-pluviatolide synthase
IUBMB Comments
The enzyme, characterized from the plants Sinopodophyllum hexandrum and Podophyllum peltatum, catalyses the formation of a methylenedioxy-bridge. It is involved in the biosynthesis of podophyllotoxin, a non-alkaloid toxin lignan whose derivatives are important anticancer drugs.
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Release 2023.1 (January 2023)
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