Information on EC 1.1.1.63 - testosterone 17beta-dehydrogenase

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EC Tree 1 Oxidoreductases 1.1 Acting on the CH-OH group of donors 1.1.1 With NAD⁺ or NADP⁺ as acceptor 1.1.1.63 testosterone 17beta-dehydrogenase

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GENERAL INFORMATION

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

malfunction

Homo sapiens

AKR1C3 knockdown is accomplished in cultured adrenal cells (H295R) using small interfering RNA. Decreasing adrenal cell expression of AKR1C3 mRNA and protein inhibit testosterone production in the H295R adrenal cell line