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Reference on EC 1.1.1.44 - phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating)

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Rippa, M.; Picco, C.; Signorini, M.; Pontremoli, S.
Evidence for a tyrosine residue at the triphosphopyridine nucleotide-binding site of 6-phosphogluconate dehydrogenase
Arch. Biochem. Biophys.
147
487-492
1971
Cyberlindnera jadinii
Manually annotated by BRENDA team
Emundson, T.D.; Ashworth, J.M.
6-phosphogluconate dehydrogenase and the assay of uridine diphosphate glucose pyrophosphorylase in the cellular slime mould Dictyostelium discoideum
Biochem. J.
126
593-600
1972
Dictyostelium discoideum
Manually annotated by BRENDA team
Beitner, R.; Naor, Z.
The effect of adenine nucleotides and dehydroepiandrosterone on the isoenzymes of NADP+-and NAD+-glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase from rat adipose tissue
Biochim. Biophys. Acta
286
437-440
1972
Rattus norvegicus
Manually annotated by BRENDA team
Procsal, D.; Holten, D.
Purification and properties of rat liver 6-phosphogluconate dehydrogenase. Activity at normal in vivo concentration
Biochemistry
11
1310-1314
1972
Mus musculus, Ovis aries, Rattus norvegicus, Rattus norvegicus Sprague-Dawley
Manually annotated by BRENDA team
Schnarrenberger, C.; Oeser, A.; Tolbert, N.E.
Two isozymes each of glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase in spinach leaves
Arch. Biochem. Biophys.
154
438-448
1973
Spinacia oleracea
Manually annotated by BRENDA team
Dyson, J.E.D.; D'Orazio, R.E.; Hanson, W.H.
Sheep liver 6-phosphogluconate dehydrogenase: Isolation procedure and effect of pH, ionic strength, and metal ions on the kinetic parameters
Arch. Biochem. Biophys.
154
623-635
1973
Cyberlindnera jadinii, Ovis aries, Rattus norvegicus
Manually annotated by BRENDA team
Dyson, J.E.D.; D'Orazio, R.E.
Sheep liver 6-phosphogluconate dehydrogenase. Inhibition by nucleoside phosphates and by other metabolic intermediates
J. Biol. Chem.
248
5428-5435
1973
Ovis aries
Manually annotated by BRENDA team
Scott, W.A.; Abramsky, T.
Neurospora 6-phosphogluconate dehydrogenase. I. Purification and characterization of the wild type enzyme
J. Biol. Chem.
248
3535-3544
1973
Cyberlindnera jadinii, Ovis aries, Neurospora crassa
Manually annotated by BRENDA team
Scott, W.A.; Abramsky, T.
Neurospora 6-phosphogluconate dehydrogenase. II. Properties and two purified mutant enzymes
J. Biol. Chem.
248
3542-3545
1973
Neurospora crassa
Manually annotated by BRENDA team
Silverberg, M.; Dalziel, K.
Crystalline 6-phosphogluconate dehydrogenase from sheep liver
Eur. J. Biochem.
38
229-238
1973
Cyberlindnera jadinii, Ovis aries, Rattus norvegicus
Manually annotated by BRENDA team
Pearse, B.M.F.; Harris, J.I.
6-Phosphogluconate dehydrogenase from Bacillus stearothermophilus
FEBS Lett.
38
49-52
1973
Geobacillus stearothermophilus, Cyberlindnera jadinii, Homo sapiens, Geobacillus stearothermophilus NCA 1503
Manually annotated by BRENDA team
Rippa, M.; Signorini, M.; Dallocchio, F.
A multiple role for the coenzyme in the mechanism of action of 6-phosphogluconate dehydrogenase
J. Biol. Chem.
248
4920-4925
1973
Saccharomyces cerevisiae, Cyberlindnera jadinii, Sus scrofa
Manually annotated by BRENDA team
Veronese, F.M.; Boccu, E.; Fontana, A.; Benassi, C.A.; Scoffone, E.
Isolation and some properties of 6-phosphogluconate dehydrogenase from Bacillus stearothermophilus
Biochim. Biophys. Acta
334
31-44
1974
Geobacillus stearothermophilus, Cyberlindnera jadinii, Homo sapiens, Neurospora crassa, Rattus norvegicus, Geobacillus stearothermophilus NCA 1503
-
Manually annotated by BRENDA team
Pearse, B.M.F.; Rosemeyer, M.A.
Human 6-phosphogluconate dehydrogenase. Purification of the erythrocyte enzyme and the influence of ions and NADPH on its activity
Eur. J. Biochem.
42
213-223
1974
Ovis aries, Homo sapiens
Manually annotated by BRENDA team
Pearse, B.M.F.; Rosemeyer, M.A.
The molecular weight and subunit structure of human erythrocyte 6-phosphogluconate dehydrogenase
Eur. J. Biochem.
42
225-235
1974
Cyberlindnera jadinii, Drosophila sp. (in: flies), Ovis aries, Homo sapiens, Rattus norvegicus
Manually annotated by BRENDA team
King, J.
6-Phosphogluconat-dehydrogenase
Methods Enzym. Anal. , 3rd Ed. (Bergmeyer, H. U. , ed. )
1
668-672
1974
Saccharomyces cerevisiae, Homo sapiens
-
Manually annotated by BRENDA team
Silverberg, M.; Dalziel, K.
6-Phospho-D-gluconate dehydrogenase from sheep liver
Methods Enzymol.
41
214-220
1975
Ovis aries, Rattus norvegicus
Manually annotated by BRENDA team
Pearse, B.M.F.; Rosemeyer, M.A.
6-Phosphogluconate from human erythrocytes
Methods Enzymol.
41
220-226
1975
Homo sapiens
Manually annotated by BRENDA team
Rippa, M.; Signorini, M.
6-Phosphogluconate dehydrogenase from Candida utilis
Methods Enzymol.
41
237-240
1975
Cyberlindnera jadinii
Manually annotated by BRENDA team
Scott, W.A.; Abramsky, T.
6-Phosphogluconate dehydrogenase from Neurospora crassa
Methods Enzymol.
41
227-231
1975
Saccharomyces cerevisiae, Neurospora crassa
Manually annotated by BRENDA team
Silverberg, M.; Dalziel, K.
Fluorescence studies of coenzyme binding to 6-phosphogluconate dehydrogenase
Arch. Biochem. Biophys.
168
646-651
1975
Ovis aries
Manually annotated by BRENDA team
Bridges, R.B.; Wittenberger, C.L.
6-Phosphogluconate dehydrogenase from Streptococcus faecalis
Methods Enzymol.
41
232-237
1975
Enterococcus faecalis
Manually annotated by BRENDA team
Bridges, R.B.; Palumbo, M.P.; Wittenberger, C.L.
Purification and properties of an NADP-specific 6-phosphogluconate dehydrogenase from Streptococcus faecalis
J. Biol. Chem.
250
6093-6100
1975
Cyberlindnera jadinii, Enterococcus faecalis, Homo sapiens, Neurospora crassa, Rattus norvegicus
Manually annotated by BRENDA team
Fontana, A.; Grandi, C.; Boccu, E.; Veronese, F.M.
Comparative thermostability of thermophilic and mesophilic 6-phosphogluconate dehydrogenase
Hoppe-Seyler's Z. Physiol. Chem.
356
1191-1193
1975
Geobacillus stearothermophilus, Escherichia coli, Geobacillus stearothermophilus NCA 1503
Manually annotated by BRENDA team
Veronese, F.M.; Boccu, E.; Fontana, A.
Denaturation of thermophilic and mesophilic 6-phosphogluconate dehydrogenase by 8 M urea
Int. J. Pept. Protein Res.
7
341-343
1975
Geobacillus stearothermophilus, Escherichia coli, Geobacillus stearothermophilus NCA 1503
Manually annotated by BRENDA team
Betts, S.A.; Mayer, R.J.
Purification and properties of 6-phosphogluconate dehydrogenase from rabbit mammary gland
Biochem. J.
151
263-270
1975
Cyberlindnera jadinii, Oryctolagus cuniculus, Escherichia coli, Ovis aries, Homo sapiens, Rattus norvegicus
Manually annotated by BRENDA team
Toews, M.L.; Kanji, M.I.; Carper, R.W.
6-Phosphogluconate dehydrogenase. Purification and kinetics
J. Biol. Chem.
251
7127-7131
1976
Cyberlindnera jadinii, Ovis aries, Homo sapiens, Rattus norvegicus, Sus scrofa
Manually annotated by BRENDA team
Veronese, F.M.; Boccu, E.; Fontana, A.
Isolation and properties of 6-phosphogluconate dehydrogenase from Escherichia coli. Some Comparisons with the thermophilic enzyme from Bacillus stearothermophilus
Biochemistry
15
4026-4033
1976
Geobacillus stearothermophilus, Cyberlindnera jadinii, Escherichia coli, Enterococcus faecalis, Neurospora crassa, Escherichia coli MRE 600
Manually annotated by BRENDA team
Adams, M.J.; Helliwell, J.R.; Bugg, C.E.
Structure of 6-phosphogluconate dehydrogenase from sheep liver at 6 A resolution
J. Mol. Biol.
112
183-197
1977
Cyberlindnera jadinii, Ovis aries
Manually annotated by BRENDA team
Dallocchio, F.; Signorini, M.; Rippa, M.
Evidence for the proximity of a cysteiyl and a tyrosyl residue in the active site of 6-phosphogluconate dehydrogenase
Arch. Biochem. Biophys.
185
57-60
1978
Cyberlindnera jadinii
Manually annotated by BRENDA team
Rippa, M.; Signorini, M.; Pernici, A.; Dallocchio, F.
Evidence for the proximity of two sulfhydryl groups at the active site of 6-phosphogluconate dehydrogenase
Arch. Biochem. Biophys.
186
406-410
1978
Cyberlindnera jadinii
Manually annotated by BRENDA team
Rippa, M.; Signorini, M.; Bellini, T.; Dallocchio, F.
The active site of 6-phosphogluconate dehydrogenase. A phosphate binding site and its surroundings
Arch. Biochem. Biophys.
189
516-523
1978
Ovis aries
Manually annotated by BRENDA team
Adams, M.J.; Archibald, I.G.; Helliwell, J.R.; Jenkins, S.E.
The crystal structure of 6-phosphogluconate dehydrogenase
Biochem. Soc. Trans.
6
1112-1115
1978
Cyberlindnera jadinii
Manually annotated by BRENDA team
Simcox, P.D.; Dennis, D.T.
6-Phosphogluconate dehydrogenase isoenzymes from the developing endosperm of Ricinus communis L.
Plant Physiol.
62
287-290
1978
Ricinus communis, Daucus carota, Vigna radiata var. radiata, Spinacia oleracea
Manually annotated by BRENDA team
Gosling, P.G.; Ross, J.D.
Characterization of glucose-6-phosphate dehydrogenase and 6-phosphogluconic acid dehydrogenase from hazel cotyledons
Phytochemistry
18
1441-1445
1979
Corylus avellana, Neurospora crassa, Vigna radiata var. radiata, Rattus norvegicus, Sus scrofa
-
Manually annotated by BRENDA team
Rippa, M.; Bellini, T.; Signorini, M.; Dallocchio, F.
The stabilization by a coenzyme analog of a conformational change induced by substrate in 6-phosphogluconate dehydrogenase
Arch. Biochem. Biophys.
196
619-623
1979
Cyberlindnera jadinii
Manually annotated by BRENDA team
Orozco de Silva, A.; Fraenkel, D.G.
The 6-phosphogluconate dehydrogenase reaction in Escherichia coli
J. Biol. Chem.
254
10237-10242
1979
Escherichia coli, Escherichia coli RW226/pLC33-5
Manually annotated by BRENDA team
Abdallah, M.A.; Adams, M.J.; Archibald, I.G.; Bielmann, J.F.; Helliwell, J.R.; Jenkins, S.E.
Binding of coenzyme and substrate and coenzyme analogues to 6-phosphogluconate dehydrogenase from sheep liver
Eur. J. Biochem.
98
121-130
1979
Ovis aries
Manually annotated by BRENDA team
Beitner, R.; Nordenberg, J.
Inhibition of 6-phosphogluconate dehydrogenase(decarboxylating) by glucose 1,6-bisphosphate
Biochim. Biophys. Acta
583
266-269
1979
Saccharomyces cerevisiae, Rattus norvegicus
Manually annotated by BRENDA team
Adkins, S.W.; Gosling, P.G.; Ross, J.D.
Glucose-6-phosphate dehydrogenase and 6-phosphogluconic acid dehydrogenase of wild oat seeds
Phytochemistry
19
2523-2525
1980
Avena fatua
-
Manually annotated by BRENDA team
Graefe, U.; Bormann, E.J.; Truckenbrodt, G.
Control by phospho-adenosinediphospho-ribose of NADP-dependent isocitrate dehydrogenase and 6-phosphogluconate dehydrogenase in Streptomyces griseus
Z. Allg. Mikrobiol.
20
607-611
1980
Saccharomyces cerevisiae, Streptomyces griseus
Manually annotated by BRENDA team
Al-Quadan, F.; Wender, S.H.; Smith, E.C.
The effect of some phenolic compounds on the activity of 6-phosphogluconate dehydrogenase from tobacco tissue cultures
Phytochemistry
20
961-964
1981
Nicotiana tabacum, Nicotiana tabacum W-38
-
Manually annotated by BRENDA team
Al-Quadan, F.; Wender, S.H.; Smith, E.C.
Comparison of tryptic peptide maps of two isoenzymes of 6-phosphogluconate dehydrogenase from tobacco tissue cultures
Phytochemistry
20
1201-1203
1981
Nicotiana tabacum, Nicotiana tabacum W-38
-
Manually annotated by BRENDA team
Bublitz, C.
Physical separation of cytoplasmic and microsomal 6-phosphogluconate dehydrogenase from rat liver
Biochem. Biophys. Res. Commun.
98
588-594
1981
Rattus norvegicus
Manually annotated by BRENDA team
Dallocchio, F.; Matteuzzi, M.; Bellini, T.
Effect of the substrate on the binding of coenzyme and coenzyme analogues to 6-phosphogluconate dehydrogenase from Candida utilis
J. Biol. Chem.
256
10778-10780
1981
Cyberlindnera jadinii
Manually annotated by BRENDA team
Jessup, W.; Dean, P.D.G.
Purification of 6-phosphogluconate dehydrogenase from Acer pseudoplatanus L. using immobilised procion red He-3B
J. Chromatogr.
219
419-426
1981
Acer pseudoplatanus, Geobacillus stearothermophilus
-
Manually annotated by BRENDA team
Wong, C.H.; Pollak, A.; McCurry, S.D.; Sue, J.M.; Knowles, J.R.; Whitesides, G.M.
Synthesis of ribulose 1,5-bisphosphate: Routes from glucose-6-phosphate (via 6-phosphogluconate) and from adenosine monophosphate (via ribose 5-phosphate)
Methods Enzymol.
89
108-121
1982
Cyberlindnera jadinii, Ovis aries
-
Manually annotated by BRENDA team
Carne, A.
Purification by dye-ligand chromatography of an NADP-dependent enzyme, 6-phosphogluconate dehydrogenase from lamb's liver
Anal. Biochem.
121
227-229
1982
Geobacillus stearothermophilus, Ovis aries
Manually annotated by BRENDA team
Dallocchio, F.; Matteuzzi, M.; Bellini, T.
Non-enzymic protein phosphorylation
Biochem. J.
203
401-404
1982
Cyberlindnera jadinii
Manually annotated by BRENDA team
Veronese, F.M.; Boccu, E.; Fontana, A.
6-Phosphogluconate dehydrogenase from Bacillus stearothermophilus
Methods Enzymol.
89
282-291
1982
Geobacillus stearothermophilus, Cyberlindnera jadinii, Escherichia coli, Geobacillus stearothermophilus NCA 1503
Manually annotated by BRENDA team
Adams, M.J.; Archibald, I.G.; Bugg, C.E.; Carne, A.; Gover, S.; Helliwell, J.R.; Pickersgill, R.W.; White, S.W.
The three dimensional structure of sheep liver 6-phosphogluconate dehydrogenase at 2.6 A resolution
EMBO J.
6
1009-1014
1983
Cyberlindnera jadinii, Ovis aries
Manually annotated by BRENDA team
Adams, M.J.; Gover, S.; Pickersgill, R.W.; Helliwell, J.R.
Structure-function relationships of NAD+ and NADP+-dependent dehydrogenases with particular reference to the three-dimensional structure of 6-phosphogluconate dehydrogenase
Biochem. Soc. Trans.
11
429-435
1983
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Miernyk, J.A.; MacDougall, P.S.; Dennis, D.T.
In vitro inhibition of the plastid and cytosolic isozymes of 6-phosphogluconate dehydrogenase from developing endosperm of Ricinus communis by fructose 2,6-bisphosphate
Plant Physiol.
76
1093-1094
1984
Saccharomyces cerevisiae, Ricinus communis, Nicotiana tabacum, Rattus norvegicus
Manually annotated by BRENDA team
Rendina, A.R.; Hermes, J.D.; Cleland, W.W.
Use of multiple isotope effects to study the mechanism of 6-phosphogluconate dehydrogenase
Biochemistry
23
6257-6262
1984
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Lubberding, H.J.; Bot, P.V.M.
The influence of temperature on glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase and the regulation of these enzymes in a mesophilic and a thermophilic cyanobacterium
Arch. Microbiol.
137
115-120
1984
Geobacillus stearothermophilus, Synechococcus sp., Synechocystis sp. PCC 6714, Synechococcus sp. PCC 6307, Synechococcus sp. PCC 6716
-
Manually annotated by BRENDA team
Veronese, F.M.; Boccu, E.; Schiavon, O.; Grandi, C.; Fontana, A.
General stability of thermophilic enzymes: Studies on 6-phosphogluconate dehydrogenase from Bacillus stearothermophilus and yeast
J. Appl. Biochem.
6
39-47
1984
Geobacillus stearothermophilus, Saccharomyces cerevisiae, Geobacillus stearothermophilus NCA 1503
Manually annotated by BRENDA team
Dallocchio, F.; Matteuzzi, M.; Bellini, T.
Half-site reactivity in 6-phosphogluconate dehydrogenase from human erythrocytes
Biochem. J.
227
305-310
1985
Cyberlindnera jadinii, Ovis aries, Homo sapiens
Manually annotated by BRENDA team
Sawa, Y.; Suzuki, K.; Ochiai, H.
Purification and characterization of 6-phosphogluconate dehydrogenase from Phormidium sp.
Agric. Biol. Chem.
49
2543-2549
1985
Geobacillus stearothermophilus, Cyberlindnera jadinii, Escherichia coli, Enterococcus faecalis, Neurospora crassa, Phormidium sp., Rattus norvegicus, Synechococcus sp., Synechococcus sp. PCC 6307, Synechococcus sp. PCC 6716
-
Manually annotated by BRENDA team
Topham, C.M.; Dalziel, K.
Chemical modification of sheep-liver 6-phosphogluconate dehydrogenase by diethylpyrocarbonate
Eur. J. Biochem.
155
87-94
1986
Cyberlindnera jadinii, Ovis aries
Manually annotated by BRENDA team
Topham, C.M.; Matthews, B.; Dalziel, K.
Kinetic studies of 6-phosphogluconate dehydrogenase from sheep liver
Eur. J. Biochem.
156
555-567
1986
Cyberlindnera jadinii, Ovis aries
Manually annotated by BRENDA team
Sugimoto, S.I.; Shiho, I.
Regulation of 6-phosphogluconate dehydrogenase in Brevibacterium flavum
Agric. Biol. Chem.
51
1257-1263
1987
[Brevibacterium] flavum, Enterococcus faecalis
-
Manually annotated by BRENDA team
Hansen, R.J.; Jungermann, K.
Sex differences in the control of glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase
Biol. Chem. Hoppe-Seyler
368
955-962
1987
Rattus norvegicus, Rattus norvegicus Wistar
Manually annotated by BRENDA team
del mar Medina-Puerta, M.; Gallego-Iniesta, M.; Garido-Pertierra, A.
Kinetic analysis of 6-phosphogluconate dehydrogenase from bass liver: Effects of temperature and pH on its catalytic function
Arch. Biochem. Biophys.
262
130-141
1988
Carassius carassius, Dicentrarchus labrax
Manually annotated by BRENDA team
Kletsova, L.V.; Kiryukhin, M.Y.; Chistoserdov, A.Y.; Tsygankov, Y.D.
Glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase from Methylobacillus flagellatum
Methods Enzymol.
188
335-339
1990
Methylobacillus flagellatus
-
Manually annotated by BRENDA team
Sokolov, A.P.; Trotsenko, Y.A.
Glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase from Arthrobacter globiformis
Methods Enzymol.
188
339-345
1990
Arthrobacter globiformis, Arthrobacter globiformis VKM B-175
-
Manually annotated by BRENDA team
Hanau, S.; Dallocchio, F.; Rippa, M.
NADPH activates a decarboxylation reaction catalyzed by lamb liver 6-phosphogluconate dehydrogenase
Biochim. Biophys. Acta
1122
273-277
1992
Cyberlindnera jadinii, Ovis aries, Homo sapiens
Manually annotated by BRENDA team
Ishida, S.; Ashihara, H.
Isoenzymes of phosphogluconate dehydrogenase (decarboxylating) from suspension-cultured Cataranthus roseus cells
Phytochemistry
33
1307-1311
1993
Acer pseudoplatanus, Ricinus communis, Catharanthus roseus, Daucus carota, Glycine max, Vigna radiata, Pisum sativum, Spinacia oleracea, Catharanthus roseus B/S
-
Manually annotated by BRENDA team
Berdis, A.J.; Cook, P.F.
Overall kinetic mechanism of 6-phosphogluconate dehydrogenase from Candida utilis
Biochemistry
32
2036-2040
1993
Leuconostoc mesenteroides, Cyberlindnera jadinii, Haemophilus influenzae, Ovis aries, Homo sapiens, Rattus norvegicus
Manually annotated by BRENDA team
Berdis, A.J.; Cook, P.F.
Chemical mechanism of 6-phosphogluconate dehydrogenase from Candida utilis from pH studies
Biochemistry
32
2041-2046
1993
Cyberlindnera jadinii
Manually annotated by BRENDA team
Berdis, A.J.; Cook, P.F.
The 2'-phosphate of NADP is critical for optimum productive binding to 6-phosphogluconate dehydrogenase from Candida utilis
Arch. Biochem. Biophys.
305
551-558
1993
Cyberlindnera jadinii, Ovis aries
Manually annotated by BRENDA team
Corpas, F.J.; Garcia-Salguero, L.; Barroso, J.B.; Aranda, F.; Lupianez, J.A.
Kinetic properties of hexose-monophosphate dehydrogenases. II. Isolation and partial purification of 6-phosphogluconate dehydrogenase from rat liver and kidney cortex
Mol. Cell. Biochem.
144
97-104
1995
Cyberlindnera jadinii, Gallus sp., Homo sapiens, Rattus norvegicus, Rattus norvegicus Wistar
Manually annotated by BRENDA team
Signorini, M.; Bregoli, A.M.; Caselli, L.; Bergamini, C.M.
Purification and properties of 6-phosphogluconate dehydrogenase from beet leaves
Biochem. Mol. Biol. Int.
35
669-675
1995
Beta vulgaris
Manually annotated by BRENDA team
Ganea, E.; Harding, J.J.
Inhibition of 6-phosphogluconate dehydrogenase by carbamylation and protection by alpha-crystallin, a chaperone-like protein
Biochem. Biophys. Res. Commun.
222
626-631
1996
Homo sapiens
Manually annotated by BRENDA team
Price, N.E.; Cook, P.F.
Kinetic and chemical mechanisms of the sheep liver 6-phosphogluconate dehydrogenase
Arch. Biochem. Biophys.
336
215-223
1996
Ovis aries
Manually annotated by BRENDA team
Phillips, C.; Dohnalek, J.; Barrett, M.P.; Adams, M.J.
A 2.8 A resolution structure of 6-phosphogluconate dehydrogenase from the protozoan parasite Trypanosoma brucei: Comparison with the sheep enzyme accounts for differences in activity with coenzyme and substrate analogues
J. Mol. Biol.
25
667-681
1998
Ovis aries, Trypanosoma brucei (P31072)
Manually annotated by BRENDA team
Tetaud, E.; Hall, D.R.; Gourley, D.G.; Leonard, G.A.; Arkison, S.; Barrett, M.P.; Hunter, W.N.
Crystallization and preliminary x-ray diffraction studies of 6-phosphogluconate dehydrogenase from Lactococcus lactis
Acta Crystallogr. Sect. D
54
1422-1424
1998
Lactococcus lactis
Manually annotated by BRENDA team
Tsai, C.S.; Chen, Q.
Purification and kinetic characterization of 6-phosphogluconate dehydrogenase from Schizosaccharomyces pombe
Biochem. Cell Biol.
76
637-644
1998
Gluconobacter oxydans, Leuconostoc mesenteroides, Cyberlindnera jadinii, Dicentrarchus labrax, Ovis aries, Neurospora crassa, Pseudomonas sp., Salmonella enterica subsp. enterica serovar Typhimurium, Schizosaccharomyces pombe
Manually annotated by BRENDA team
Chooback, L.; Price, N.E.; Karsten, W.E.; Nelson, J.; Sundstrom, P.; Cook, P.F.
Cloning, expression, purification, and characterization of the 6-phosphogluconate dehydrogenase from sheep liver
Protein Expr. Purif.
13
251-258
1998
Cyberlindnera jadinii, Escherichia coli, Escherichia coli JM109 M15, Ovis aries
Manually annotated by BRENDA team
Rippa, M.; Giovannini, P.P.; Barrett, M.P.; Dallocchio, F.; Hanau, S.
6-Phosphogluconate dehydrogenase: The mechanism of action investigated by a comparison of the enzyme from different species
Biochim. Biophys. Acta
1429
83-92
1998
Cyberlindnera jadinii, Ovis aries, Homo sapiens, Trypanosoma brucei
Manually annotated by BRENDA team
Moritz, B.; Striegel, K.; de Graaf, A.A.; Sahm, H.
Kinetic properties of the glucose-6-phosphate and 6-phosphogluconate dehydrogenases from Corynebacterium glutamicum and their application for predicting pentose phosphate pathway flux in vivo
Eur. J. Biochem.
267
3442-3452
2000
Acer pseudoplatanus, Gluconobacter oxydans, Corynebacterium glutamicum, [Brevibacterium] flavum, Saccharomyces cerevisiae, [Candida] boidinii, Corynebacterium glutamicum ssp. flavum, Escherichia coli, Ovis aries, Pseudomonas sp., Pseudomonas sp. C
Manually annotated by BRENDA team
Kato, N.; Sahm, H.; Schutte, H.; Wagner, F.
Purification and properties of glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase from a methanol-utilizing yeast, Candida boidinii
Biochim. Biophys. Acta
566
1-11
1979
Saccharomyces cerevisiae, [Candida] boidinii, Ovis aries
Manually annotated by BRENDA team
Sindelar, L.; Sindelarova, M.
Glucose-6-phosphate dehydrogenase/6-phosphogluconate dehydrogenase ratio and the glucose-6-phosphate, 6-phosphogluconate and fructose-6-phosphate contents in tobacco plants infected with potato virus Y
Biol. Plant.
45
575-580
2002
Nicotiana tabacum
-
Manually annotated by BRENDA team
Pasti, C.; Rinaldi, E.; Cervellati, C.; Dallocchio, F.; Hardre, R.; Salmon, L.; Hanau, S.
Sugar derivatives as new 6-phosphogluconate dehydrogenase inhibitors selective for the parasite Trypanosoma brucei
Bioorg. Med. Chem.
11
1207-1214
2003
Ovis aries (P00349), Trypanosoma brucei (P31072)
Manually annotated by BRENDA team
Pankiewicz, A.; Sledzinski, T.; Nogalska, A.; Swierczynski, J.
Tissue specific, sex and age-related differences in the 6-phosphogluconate dehydrogenase gene expression
Int. J. Biochem. Cell Biol.
35
235-245
2003
Rattus norvegicus
Manually annotated by BRENDA team
Zamboni, N.; Fischer, E.; Laudert, D.; Aymerich, S.; Hohmann, H.P.; Sauer, U.
The Bacillus subtilis yqjI gene encodes the NADP+-dependent 6-P-gluconate dehydrogenase in the pentose phosphate pathway
J. Bacteriol.
186
4528-4534
2004
Bacillus subtilis (P80859), Bacillus subtilis
Manually annotated by BRENDA team
Akyuez, M.; Erat, M.; Ciftci, M.; Guemuestekin, K.; Bakan, N.
Effects of some antibiotics on human erythrocyte 6-phosphogluconate dehydrogenase: an in vitro and in vivo study
J. Enzyme Inhib. Med. Chem.
19
361-365
2004
Homo sapiens, Rattus norvegicus
Manually annotated by BRENDA team
Dardonville, C.; Rinaldi, E.; Barrett, M.P.; Brun, R.; Gilbert, I.H.; Hanau, S.
Selective inhibition of Trypanosoma brucei 6-phosphogluconate dehydrogenase by high-energy intermediate and transition-state analogues
J. Med. Chem.
47
3427-3437
2004
Ovis aries, Leishmania donovani, Plasmodium falciparum, Trypanosoma brucei, Trypanosoma cruzi
Manually annotated by BRENDA team
Esteve, M.I.; Cazzulo, J.J.
The 6-phosphogluconate dehydrogenase from Trypanosoma cruzi: the absence of two inter-subunit salt bridges as a reason for enzyme instability
Mol. Biochem. Parasitol.
133
197-207
2004
Trypanosoma cruzi (Q6WAT5)
Manually annotated by BRENDA team
Huang, J.; Zhang, H.; Wang, J.; Yang, J.
Molecular cloning and characterization of rice 6-phosphogluconate dehydrogenase gene that is up-regulated by salt stress
Mol. Biol. Rep.
30
223-227
2003
Oryza sativa (Q9LI00)
Manually annotated by BRENDA team
Ciftci, M.; Beydemir, S.; Yilmaz, H.; Bakan, E.
Effects of some drugs on rat erythrocyte 6-phosphogluconate dehydrogenase: an in vitro and in vivo study
Pol. J. Pharmacol.
54
275-280
2002
Rattus norvegicus
Manually annotated by BRENDA team
Corpas, F.J.; Barroso, J.B.; Sandalio, L.M.; Distefano, S.; Palma, J.M.; Lupianez, J.A.; del Rio, L.A.
A dehydrogenase-mediated recycling system of NADPH in plant peroxisomes
Biochem. J.
330
777-784
1998
Pisum sativum
-
Manually annotated by BRENDA team
Rho, H.K.; Park, J.; Suh, J.H.; Kim, J.B.
Transcriptional regulation of mouse 6-phosphogluconate dehydrogenase by ADD1/SREBP1c
Biochem. Biophys. Res. Commun.
332
288-296
2005
Mus musculus
Manually annotated by BRENDA team
Goulielmos, G.N.; Cosmidis, N.; Eliopoulos, E.; Loukas, M.; Zouros, E.
Cloning and structural characterization of the 6-phosphogluconate dehydrogenase locus of the medfly Ceratitis capitata and the olive fruit fly Bactrocera oleae
Biochem. Biophys. Res. Commun.
341
721-727
2006
Ceratitis capitata, Bactrocera oleae
Manually annotated by BRENDA team
Cervellati, C.; Dallocchio, F.; Bergamini, C.M.; Cook, P.F.
Role of methionine-13 in the catalytic mechanism of 6-phosphogluconate dehydrogenase from sheep liver
Biochemistry
44
2432-2440
2005
Ovis aries (P00349)
Manually annotated by BRENDA team
Li, L.; Zhang, L.; Cook, P.F.
Role of the S128, H186, and N187 triad in substrate binding and decarboxylation in the sheep liver 6-phosphogluconate dehydrogenase reaction
Biochemistry
45
12680-12686
2006
Ovis aries (P00349)
Manually annotated by BRENDA team
Daniely, D.; Portnoi, M.; Shagan, M.; Porgador, A.; Givon-Lavi, N.; Ling, E.; Dagan, R.; Mizrachi Nebenzahl, Y.
Pneumococcal 6-phosphogluconate-dehydrogenase, a putative adhesin, induces protective immune response in mice
Clin. Exp. Immunol.
144
254-263
2006
Streptococcus pneumoniae, Streptococcus pneumoniae WU2
Manually annotated by BRENDA team
Sledzinski, T.; Nogalska, A.; Hebanowska, A.; Klimek, J.; Swierczynski, J.
Gender- and age-related changes in 6-phosphogluconate dehydrogenase gene expression in white adipose tissue of rats (Rattus norvegicus) are not related to serum testosterone concentration
Comp. Biochem. Physiol. B
144B
70-76
2006
Rattus norvegicus
-
Manually annotated by BRENDA team
Li, L.; Dworkowski, F.S.; Cook, P.F.
Importance in catalysis of the 6-phosphate-binding site of 6-phosphogluconate in sheep liver 6-phosphogluconate dehydrogenase
J. Biol. Chem.
281
25568-25576
2006
Ovis aries (P00349)
Manually annotated by BRENDA team
Wang, J.; Li, S.
Catalytic mechanism of 6-phosphogluconate dehydrogenase: a theoretical investigation
J. Phys. Chem. B
110
7029-7035
2006
Ovis aries (P00349)
Manually annotated by BRENDA team
Erat, M.
Purification of 6-phosphogluconate dehydrogenase from chicken liver and investigation of some kinetic properties
Prep. Biochem. Biotechnol.
35
53-69
2005
Gallus gallus
Manually annotated by BRENDA team
Ceyhan, D.; Dani?an, A.; O?ue?, I.H.; Ozer, N.
Purification and kinetic properties of 6-phosphogluconate dehydrogenase from rat small intestine
Protein J.
24
293-301
2005
Rattus norvegicus
Manually annotated by BRENDA team
Chograni, H.; Messaoud, C.; Boussaid, M.
Genetic diversity and population structure in Tunisian Lavandula stoechas L. and Lavandula multifida L. (Lamiaceae)
Biochem. Syst. Ecol.
36
349-359
2008
Lavandula stoechas, Lavandula multifida
-
Manually annotated by BRENDA team
Shin, E.S.; Park, J.; Shin, J.M.; Cho, D.; Cho, S.Y.; Shin, D.W.; Ham, M.; Kim, J.B.; Lee, T.R.
Catechin gallates are NADP+-competitive inhibitors of glucose-6-phosphate dehydrogenase and other enzymes that employ NADP+ as a coenzyme
Bioorg. Med. Chem.
16
3580-3586
2008
Mus musculus
Manually annotated by BRENDA team
Maruyama, S.; Misawa, K.; Iseki, M.; Watanabe, M.; Nozaki, H.
Origins of a cyanobacterial 6-phosphogluconate dehydrogenase in plastid-lacking eukaryotes
BMC Evol. Biol.
8
151
2008
Euglena gracilis (B2NIV9), Peranema trichophorum (B2NIW0), Diplonema papillatum (B2NIW1), Cyanophora paradoxa (B2NIW2), Gloeochaete wittrockiana (B2NIW3), Cyanoptyche gloeocystis (B2NIW4)
Manually annotated by BRENDA team
He, W.; Wang, Y.; Liu, W.; Zhou, C.
Crystal structure of Saccharomyces cerevisiae 6-phosphogluconate dehydrogenase Gnd1
BMC Struct. Biol.
7
38
2007
Saccharomyces cerevisiae (P38720), Saccharomyces cerevisiae
Manually annotated by BRENDA team
Ruda, G.F.; Alibu, V.P.; Mitsos, C.; Bidet, O.; Kaiser, M.; Brun, R.; Barrett, M.P.; Gilbert, I.H.
Synthesis and biological evaluation of phosphate prodrugs of 4-phospho-D-erythronohydroxamic acid, an inhibitor of 6-phosphogluconate dehydrogenase
ChemMedChem
2
1169-1180
2007
Trypanosoma brucei
Manually annotated by BRENDA team
Sundaramoorthy, R.; Iulek, J.; Barrett, M.P.; Bidet, O.; Ruda, G.F.; Gilbert, I.H.; Hunter, W.N.
Crystal structures of a bacterial 6-phosphogluconate dehydrogenase reveal aspects of specificity, mechanism and mode of inhibition by analogues of high-energy reaction intermediates
FEBS J.
274
275-286
2007
Trypanosoma brucei, Lactococcus lactis (P96789), Lactococcus lactis
Manually annotated by BRENDA team
Adem, S.; Ciftci, M.
Effects of some drugs on human erythrocyte 6-phosphogluconate dehydrogenase: an in vitro study
J. Enzyme Inhib. Med. Chem.
22
751-754
2007
Homo sapiens
Manually annotated by BRENDA team
Ciftci, M.; Yilmaz, H.; Coban, T.A.; Gul, M.; Gumustekin, K.; Dane, S.
Effects of nicotine and vitamin E on 6-phosphogluconate dehydrogenase activity in some rat tissues in vivo and in vitro
J. Enzyme Inhib. Med. Chem.
23
261-265
2008
Rattus norvegicus
Manually annotated by BRENDA team
Bulbul, M.; Erat, M.
Investigation of the effects of some sulfonamide derivatives on the activities of glucose-6-phosphate dehydrogenase, 6-phospho gluconate dehydrogenase and glutathione reductase from human erythrocytes
J. Enzyme Inhib. Med. Chem.
23
418-423
2008
Homo sapiens
Manually annotated by BRENDA team
Hou, F.; Huang, J.; Yu, S.; Zhang, H.
The 6-phosphogluconate dehydrogenase genes are responsive to abiotic stresses in rice
J. Integr. Plant Biol.
49
655-663
2007
Oryza sativa
-
Manually annotated by BRENDA team
Domagala, A.; Pulido, S.; Kurpisz, M.; Herr, J.C.
Application of proteomic methods for identificaiton of sperm immunogenic antigens
Mol. Hum. Reprod.
13
437-444
2007
Homo sapiens
Manually annotated by BRENDA team
Tan, C.; Fu, S.; Liu, M.; Jin, M.; Liu, J.; Bei, W.; Chen, H.
Cloning, expression and characterization of a cell wall surface protein, 6-phosphogluconate-dehydrogenase, of Streptococcus suis serotype 2
Vet. Microbiol.
130
363-370
2008
Streptococcus suis (A4VX60), Streptococcus suis
Manually annotated by BRENDA team
Cameron, S.; Martini, V.P.; Iulek, J.; Hunter, W.N.
Geobacillus stearothermophilus 6-phosphogluconate dehydrogenase complexed with 6-phosphogluconate
Acta Crystallogr. Sect. F
65
450-454
2009
Geobacillus stearothermophilus
Manually annotated by BRENDA team
Cervellati, C.; Li, L.; Andi, B.; Guariento, A.; Dallocchio, F.; Cook, P.F.
Proper orientation of the nicotinamide ring of NADP is important for the precatalytic conformational change in the 6-phosphogluconate dehydrogenase reaction
Biochemistry
47
1862-1870
2008
Ovis aries
Manually annotated by BRENDA team
Porco, A.; Gamero, E.E.; Mylonas, E.; Isturiz, T.
Gluconate as suitable potential reduction supplier in Corynebacterium glutamicum: cloning and expression of gntP and gntK in Escherichia coli
Biol. Res.
41
349-358
2008
Corynebacterium glutamicum (Q6NHC5)
Manually annotated by BRENDA team
Tan, C.; Liu, M.; Liu, J.; Yuan, F.; Fu, S.; Liu, Y.; Jin, M.; Bei, W.; Chen, H.
Vaccination with Streptococcus suis serotype 2 recombinant 6PGD protein provides protection against S. suis infection in swine
FEMS Microbiol. Lett.
296
78-83
2009
Streptococcus suis
Manually annotated by BRENDA team
Chen, Y.Y.; Ko, T.P.; Chen, W.H.; Lo, L.P.; Lin, C.H.; Wang, A.H.
Conformational changes associated with cofactor/substrate binding of 6-phosphogluconate dehydrogenase from Escherichia coli and Klebsiella pneumoniae: Implications for enzyme mechanism
J. Struct. Biol.
169
25-35
2010
Escherichia coli (P00350), Klebsiella pneumoniae (Q762L5), Klebsiella pneumoniae NTUH-K2044 (Q762L5)
Manually annotated by BRENDA team
Wang, Y.; Zhang, Y.H.
Overexpression and simple purification of the Thermotoga maritima 6-phosphogluconate dehydrogenase in Escherichia coli and its application for NADPH regeneration
Microb. Cell Fact.
8
30
2009
Thermotoga maritima
Manually annotated by BRENDA team
Leyva, L.A.; Bashan, Y.
Activity of two catabolic enzymes of the phosphogluconate pathway in mesquite roots inoculated with Azospirillum brasilense Cd
Plant Physiol. Biochem.
46
898-904
2008
Azospirillum brasilense
Manually annotated by BRENDA team
Yin, Y.; Ashihara, H.
Expression of glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase isoform genes in suspension-cultured Arabidopsis thaliana cells
Z. Naturforsch. C
63
713-720
2008
Arabidopsis thaliana
Manually annotated by BRENDA team
Laliotis, G.P.; Trivizaki, S.; Bizelis, I.; Charismiadou, M.A.; Rogdakis, E.
Enzymatic and mRNA transcript response of ovine 6-phosphogluconate dehydrogenase (6PGD) in respect to different weights from weaning to four months of age
Anim. Biotechnol.
21
149-155
2010
Ovis aries
Manually annotated by BRENDA team
Ruda, G.F.; Campbell, G.; Alibu, V.P.; Barrett, M.P.; Brenk, R.; Gilbert, I.H.
Virtual fragment screening for novel inhibitors of 6-phosphogluconate dehydrogenase
Bioorg. Med. Chem.
18
5056-5062
2010
Trypanosoma brucei
Manually annotated by BRENDA team
Hanau, S.; Montin, K.; Cervellati, C.; Magnani, M.; Dallocchio, F.
6-Phosphogluconate dehydrogenase mechanism: evidence for allosteric modulation by substrate
J. Biol. Chem.
285
21366-21371
2010
Cyberlindnera jadinii
Manually annotated by BRENDA team
Strijbis, K.; van den Burg, J.; Visser, W.F.; van den Berg, M.; Distel, B.
Alternative splicing directs dual localization of Candida albicans 6-phosphogluconate dehydrogenase to cytosol and peroxisomes
FEMS Yeast Res.
12
61-68
2012
Candida albicans
Manually annotated by BRENDA team
Hanau, S.; dEmpaire, L.P.; Capone, I.; Alberighi, S.; Montioli, R.; Dallocchio, F.
Evidence for dimer/tetramer equilibrium in Trypanosoma brucei 6-phosphogluconate dehydrogenase
Biochim. Biophys. Acta
1834
2647-2652
2013
Trypanosoma brucei
Manually annotated by BRENDA team
Zera, A.J.; Wehrkamp, C.; Schilder, R.; Black, C.; Gribben, P.
Purification and characterization of 6-phosphogluconate dehydrogenase from the wing-polymorphic cricket, Gryllus firmus, and assessment of causes of morph-differences in enzyme activity
Comp. Biochem. Physiol. B
172-173
29-38
2014
Gryllus firmus
Manually annotated by BRENDA team
Sun, L.D.; Luo, Z.; Hu, W.; Zhuo, M.Q.; Zheng, J.L.; Chen, Q.L.; Liang, X.F.; Xiong, B.X.
Purification and characterization of 6-phosphogluconate dehydrogenase (6-PGD) from grass carp (Ctenopharyngodon idella) hepatopancreas
Indian J. Biochem. Biophys.
50
554-561
2013
Ctenopharyngodon idella
Manually annotated by BRENDA team
Budak, H.; Ceylan, H.; Kocpinar, E.F.; Gonul, N.; Erdogan, O.
Expression of glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase in oxidative stress induced by long-term iron toxicity in rat liver
J. Biochem. Mol. Toxicol.
28
217-223
2014
Rattus norvegicus
Manually annotated by BRENDA team
Demirdag, R.; Comakli, V.; Ozkaya, A.; Sahin, Z.; Dag, U.; Yerlikaya, E.; Kuzu, M.
Examination of changes in enzyme activities of erythrocyte glucose 6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase in rats given naringenin and lead acetate
J. Biochem. Mol. Toxicol.
29
43-47
2015
Rattus norvegicus
Manually annotated by BRENDA team
Spielbauer, G.; Li, L.; Roemisch-Margl, L.; Do, P.T.; Fouquet, R.; Fernie, A.R.; Eisenreich, W.; Gierl, A.; Settles, A.M.
Chloroplast-localized 6-phosphogluconate dehydrogenase is critical for maize endosperm starch accumulation
J. Exp. Bot.
64
2231-2242
2013
Zea mays
Manually annotated by BRENDA team
Dreifke, M.; Fried, D.; Brieler, F.; Froeba, M.
Kinetic investigations of 6-phosphogluconate dehydrogenase confined in mesoporous silica
J. Mol. Catal. B
132
5-15
2016
Geobacillus stearothermophilus
-
Manually annotated by BRENDA team
Sandoval, J.M.; Arenas, F.A.; Garcia, J.A.; Diaz-Vasquez, W.A.; Valdivia-Gonzalez, M.; Sabotier, M.; Vasquez, C.C.
Escherichia coli 6-phosphogluconate dehydrogenase aids in tellurite resistance by reducing the toxicant in a NADPH-dependent manner
Microbiol. Res.
177
22-27
2015
Escherichia coli, Escherichia coli BW25113
Manually annotated by BRENDA team
Lin, R.; Elf, S.; Shan, C.; Kang, H.B.; Ji, Q.; Zhou, L.; Hitosugi, T.; Zhang, L.; Zhang, S.; Seo, J.H.; Xie, J.; Tucker, M.; Gu, T.L.; Sudderth, J.; Jiang, L.; Mitsche, M.; DeBerardinis, R.J.; Wu, S.; Li, Y.; Mao, H.; Chen, P.R.; Wang, D.; Chen, G.Z.; Hurwitz, S.J.; Lonial, S.; Arellano, M.L.; Khoury, H.J.; Khuri, F.R.
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling
Nat. Cell Biol.
17
1484-1496
2015
Homo sapiens
Manually annotated by BRENDA team
Lutterbey, M.C.; von Schaewen, A.
Analysis of homo- and hetero-dimerization among the three 6-phosphogluconate dehydrogenase isoforms of Arabidopsis
Plant Signal. Behav.
11
e1207034
2016
Arabidopsis thaliana
Manually annotated by BRENDA team
Chan, B.; Sukhatme, V.P.
One-step purification of soluble recombinant human 6-phosphogluconate dehydrogenase from Escherichia coli
Protein Expr. Purif.
92
62-66
2013
Homo sapiens (P52209), Homo sapiens
Manually annotated by BRENDA team
Huang, R.; Chen, H.; Zhong, C.; Kim, J.E.; Zhang, Y.H.
High-throughput screening of coenzyme preference change of thermophilic 6-phosphogluconate dehydrogenase from NADP+ to NAD+
Sci. Rep.
6
32644
2016
Moorella thermoacetica (A0A1J5NX54)
Manually annotated by BRENDA team
Chen, H.; Zhu, Z.; Huang, R.; Zhang, Y.P.
Coenzyme engineering of a hyperthermophilic 6-phosphogluconate dehydrogenase from NADP+ to NAD+ with its application to biobatteries
Sci. Rep.
6
36311
2016
Thermotoga maritima (Q9WYR9)
Manually annotated by BRENDA team
Fernandez-Fernandez, A.D.; Corpas, F.J.
In silico analysis of Arabidopsis thaliana peroxisomal 6-phosphogluconate dehydrogenase
Scientifica
2016
3482760
2016
Arabidopsis thaliana (Q9FWA3), Arabidopsis thaliana
Manually annotated by BRENDA team
Rodrigues, J.; Branco, V.; Lu, J.; Holmgren, A.; Carvalho, C.
Toxicological effects of thiomersal and ethylmercury: Inhibition of the thioredoxin system and NADP+-dependent dehydrogenases of the pentose phosphate pathway
Toxicol. Appl. Pharmacol.
286
216-223
2015
Homo sapiens
Manually annotated by BRENDA team
Huang, R.; Chen, H.; Zhong, C.; Kim, J.E.; Zhang, Y.H.
High-throughput screening of coenzyme preference change of thermophilic 6-phosphogluconate dehydrogenase from NADP+ to NAD+
Sci. Rep.
6
32644
2016
Moorella thermoacetica (Q2RIZ2)
Manually annotated by BRENDA team
Chen, H.; Zhu, Z.; Huang, R.; Zhang, Y.P.
Coenzyme engineering of a hyperthermophilic 6-phosphogluconate dehydrogenase from NADP(+) to NAD(+) with its application to biobatteries
Sci. Rep.
6
36311
2016
Thermotoga maritima (Q9WYR9)
Manually annotated by BRENDA team
Wang, Y.; Percival, Y.
Overexpression and simple purification of the Thermotoga maritima 6-phosphogluconate dehydrogenase in Escherichia coli and its application for NADPH regeneration
Microb. Cell Fact.
8
30
2009
Thermotoga maritima (Q9WYR9), Thermotoga maritima, Thermotoga maritima DSM 3109 (Q9WYR9)
Manually annotated by BRENDA team
Ma, L.; Cheng, Q.
Inhibiting 6-phosphogluconate dehydrogenase reverses doxorubicin resistance in anaplastic thyroid cancer via inhibiting NADPH-dependent metabolic reprogramming
Biochem. Biophys. Res. Commun.
498
912-917
2018
Homo sapiens (P52209)
Manually annotated by BRENDA team
Sarfraz, I.; Rasul, A.; Hussain, G.; Shah, M.A.; Zahoor, A.F.; Asrar, M.; Selamoglu, Z.; Ji, X.Y.; Adem, S.; Sarker, S.D.
6-Phosphogluconate dehydrogenase fuels multiple aspects of cancer cells From cancer initiation to metastasis and chemoresistance
Biofactors
46
550-562
2020
Homo sapiens (P52209)
Manually annotated by BRENDA team
Polat, I.H.; Tarrado-Castellarnau, M.; Bharat, R.; Perarnau, J.; Benito, A.; Cortes, R.; Sabatier, P.; Cascante, M.
Oxidative pentose phosphate pathway enzyme 6-phosphogluconate dehydrogenase plays a key role in breast cancer metabolism
Biology
10
85
2021
Homo sapiens (P52209)
Manually annotated by BRENDA team
Caliskan, B.; Oeztuerk Kesebir, A.; Demir, Y.; Akyol Salman, I.
The effect of brimonidine and proparacaine on metabolic enzymes Glucose-6-phosphate dehydrogenase, 6-phosphogluconate dehydrogenase, and glutathione reductase
Biotechnol. Appl. Biochem.
69
281-288
2022
Homo sapiens (P52209), Homo sapiens
Manually annotated by BRENDA team
Li, H.; Ericsson, M.; Rabasha, B.; Budnik, B.; Chan, S.H.; Freinkman, E.; Lewis, C.A.; Doench, J.G.; Wagner, B.K.; Garraway, L.A.; Schreiber, S.L.
6-Phosphogluconate dehydrogenase links cytosolic carbohydrate metabolism to protein secretion via modulation of glutathione levels
Cell Chem. Biol.
26
1306-1314
2019
Homo sapiens (P52209)
Manually annotated by BRENDA team
Daneshmandi, S.; Cassel, T.; Lin, P.; Higashi, R.M.; Wulf, G.M.; Boussiotis, V.A.; Fan, T.W.; Seth, P.
Blockade of 6-phosphogluconate dehydrogenase generates CD8+ effector Tcells with enhanced anti-tumor function
Cell Rep.
34
108831
2021
Mus musculus (Q9DCD0)
Manually annotated by BRENDA team
Kremp, M.; Bittner, E.; Martorana, D.; Klingenberger, A.; Stehlik, T.; Boelker, M.; Freitag, J.
Non-AUG translation initiation generates peroxisomal isoforms of 6-phosphogluconate dehydrogenase in fungi
Front. Cell Dev. Biol.
8
251
2020
Ustilago maydis (A0A0D1CRJ9), Ustilago maydis 521 (A0A0D1CRJ9)
Manually annotated by BRENDA team
Gonul Baltaci, N.; Guler, C.; Ceylan, H.; Kalin, S.N.; Adem, S.; Kocpinar, E.F.; Erdogan, O.; Budak, H.
In vitro and in vivo effects of iron on the expression and activity of glucose 6-phosphate dehydrogenase, 6-phosphogluconate dehydrogenase, and glutathione reductase in rat spleen
J. Biochem. Mol. Toxicol.
2018
e22229
2018
Rattus norvegicus (P85968)
Manually annotated by BRENDA team
Bayindir, S.; Temel, Y.; Ayna, A.; Ciftci, M.
The synthesis of N-benzoylindoles as inhibitors of rat erythrocyte glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase
J. Biochem. Mol. Toxicol.
32
e22193
2018
Rattus norvegicus (P85968)
Manually annotated by BRENDA team
Corkins, M.E.; Wilson, S.; Cocuron, J.C.; Alonso, A.P.; Bird, A.J.
The gluconate shunt is an alternative route for directing glucose into the pentose phosphate pathway in fission yeast
J. Biol. Chem.
292
13823-13832
2017
Schizosaccharomyces pombe (P78812), Schizosaccharomyces pombe ATCC 24843 (P78812)
Manually annotated by BRENDA team
Kwolek-Mirek, M.; Maslanka, R.; Molon, M.
Disorders in NADPH generation via pentose phosphate pathway influence the reproductive potential of the Saccharomyces cerevisiae yeast due to changes in redox status
J. Cell. Biochem.
120
8521-8533
2019
Saccharomyces cerevisiae (P38720), Saccharomyces cerevisiae (P53319), Saccharomyces cerevisiae BY4742 (P38720), Saccharomyces cerevisiae BY4742 (P53319)
Manually annotated by BRENDA team
Corpas, F.J.; Gonzalez-Gordo, S.; Palma, J.M.
Nitric oxide and hydrogen sulfide modulate the NADPH-generating enzymatic system in higher plants
J. Exp. Bot.
72
830-847
2021
Arabidopsis thaliana (Q9FFR3), Arabidopsis thaliana (Q9FWA3), Arabidopsis thaliana (Q9SH69)
Manually annotated by BRENDA team
Jin, X.M.; Chang, Y.K.; Lee, J.H.; Hong, S.K.
Effects of increased NADPH concentration by metabolic engineering of the pentose phosphate pathway on antibiotic production and sporulation in Streptomyces lividans TK24
J. Microbiol. Biotechnol.
27
1867-1876
2017
Streptomyces lividans, Streptomyces lividans TK24
Manually annotated by BRENDA team
Haeussler, K.; Fritz-Wolf, K.; Reichmann, M.; Rahlfs, S.; Becker, K.
Characterization of Plasmodium falciparum 6-phosphogluconate dehydrogenase as an antimalarial drug target
J. Mol. Biol.
430
4049-4067
2018
Homo sapiens (P52209), Plasmodium falciparum (Q8IKT2), Plasmodium falciparum
Manually annotated by BRENDA team
Liu, R.; Li, W.; Tao, B.; Wang, X.; Yang, Z.; Zhang, Y.; Wang, C.; Liu, R.; Gao, H.; Liang, J.; Yang, W.
Tyrosine phosphorylation activates 6-phosphogluconate dehydrogenase and promotes tumor growth and radiation resistance
Nat. Commun.
10
991
2019
Homo sapiens (P52209), Homo sapiens
Manually annotated by BRENDA team
Bhanot, H.; Weisberg, E.L.; Reddy, M.M.; Nonami, A.; Neuberg, D.; Stone, R.M.; Podar, K.; Salgia, R.; Griffin, J.D.; Sattler, M.
Acute myeloid leukemia cells require 6-phosphogluconate dehydrogenase for cell growth and NADPH-dependent metabolic reprogramming
Oncotarget
8
67639-67650
2017
Homo sapiens (P52209)
Manually annotated by BRENDA team
Ito, S.; Osanai, T.
Single amino acid change in 6-phosphogluconate dehydrogenase from Synechocystis conveys higher affinity for NADP+ and altered mode of inhibition by NADPH
Plant Cell Physiol.
59
2452-2461
2018
Arthrospira platensis (D4ZTT4), Arthrospira platensis, Synechocystis sp. (P52208), Synechocystis sp., Arthrospira platensis NIES-39 (D4ZTT4)
Manually annotated by BRENDA team
Chen, L.; Kuai, P.; Ye, M.; Zhou, S.; Lu, J.; Lou, Y.
Overexpression of a cytosolic 6-phosphogluconate dehydrogenase gene enhances the resistance of rice to Nilaparvata lugens
Plants (Basel)
9
1529
2020
Oryza sativa Japonica Group (Q9LI00)
Manually annotated by BRENDA team
Sahin, S.
Stability evaluation of 6-phosphogluconate dehydrogenase immobilized on amino-functionalized magnetic nanoparticles
Prep. Biochem. Biotechnol.
49
590-596
2019
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Ribeiro, C.; Hennen-Bierwagen, T.; Myers, A.; Cline, K.; Settles, A.
Engineering 6-phosphogluconate dehydrogenase improves grain yield in heat-stressed maize
Proc. Natl. Acad. Sci. USA
117
33177-33185
2021
Zea mays
Manually annotated by BRENDA team