Any feedback?
Please rate this page
(enzyme.php)
(0/150)

BRENDA support

Information on EC 1.1.1.395 - 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase

for references in articles please use BRENDA:EC1.1.1.395

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
IUBMB Comments

This bacterial enzyme is involved in the 7-dehydroxylation process associated with bile acid degradation. The enzyme has very little activity with unconjugated bile acid substrates. It has similar activity with choloyl-CoA, chenodeoxycholoyl-CoA, deoxycholoyl-CoA, and lithocholoyl-CoA.

The expected taxonomic range for this enzyme is: Bacteria, Archaea

Synonyms
baia1, baia2, baia3, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
a 3alpha-hydroxy bile acid CoA ester + NAD+ = a 3-oxo bile acid CoA ester + NADH + H+
show the reaction diagram
-
-
-
-
PATHWAY SOURCE
PATHWAYS
MetaCyc
bile acid 7alpha-dehydroxylation, bile acid 7beta-dehydroxylation
Highest Expressing Human Cell Lines
Cell Line Links Gene Links