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Information on EC 1.1.1.293 - tropinone reductase I

for references in articles please use BRENDA:EC1.1.1.293

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Old data from external sources may still be available.
Please check here for current data: EC 1.1.1.206
deleted, identical to EC 1.1.1.206, tropine dehydrogenase
IUBMB Comments

This enzyme along with EC 1.1.1.236, tropinone reductase II, represents a branch point in tropane alkaloid metabolism . Tropine (the product of EC 1.1.1.293) is incorporated into hyoscyamine and scopolamine whereas pseudotropine (the product of EC 1.1.1.236) is the first specific metabolite on the pathway to the calystegines . Both enzymes are always found together in any given tropane-alkaloid-producing species, have a common substrate, tropinone, and are strictly stereospecific .

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