We're sorry, but BRENDA doesn't work properly without JavaScript. Please make sure you have JavaScript enabled in your browser settings.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
IUBMB Comments Highly specific to 3α-hydroxy derivatives of glycyrrhetinate and its analogues. Not identical to EC 1.1.1.50 3α-hydroxysteroid dehydrogenase (Si -specific).
Synonyms
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
dehydrogenase, 3alpha-hydroxyglycyrrhetinate
-
-
-
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
3alpha-hydroxyglycyrrhetinate + NADP+ = 3-oxoglycyrrhetinate + NADPH + H+
-
-
-
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
3alpha-hydroxyglycyrrhetinate:NADP+ 3-oxidoreductase
Highly specific to 3alpha-hydroxy derivatives of glycyrrhetinate and its analogues. Not identical to EC 1.1.1.50 3alpha-hydroxysteroid dehydrogenase (Si-specific).
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
3alpha-hydroxy-18alpha-glycyrrhetic acid + NADP+
3-keto-18alpha-glycyrrhetic acid + NADPH
-
Substrates: -
r
3alpha-hydroxyglycyrrhetic acid + NADP+
3-ketoglycyrrhetic acid + NADPH
3alpha-hydroxyglycyrrhetic acid + NADP+
3-ketoglycyrrhetic acid + NADPH
-
Substrates: oxidation of 3alpha-hydroxy group faster than reduction of 3-keto group, not accepted as substrates: 3beta-hydroxyglycyrrhetic acid, steroids or bile acids containing 3alpha-hydroxy or 3-keto group
r
3alpha-hydroxyglycyrrhetic acid + NADP+
3-ketoglycyrrhetic acid + NADPH
-
Substrates: oxidation of 3alpha-hydroxy group faster than reduction of 3-keto group
r
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
3alpha-hydroxyglycyrrhetic acid + NADP+
3-ketoglycyrrhetic acid + NADPH
-
Substrates: oxidation of 3alpha-hydroxy group faster than reduction of 3-keto group
r
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
0.001
3-Ketoglycyrrhetic acid
-
-
0.002
3alpha-Hydroxyglycyrrhetic acid
-
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
0.00002
-
enzyme activity in microsomal fraction of liver homogenate
additional information
gastrointestinal bacteria
-
0.002 micromol/min/mg wet weight of gastrointestinal content
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
6
-
reduction of 3-keto group
8
-
oxidation of 3alpha-hydroxy group
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
gastrointestinal bacteria
of rat caecum
-
-
brenda
-
-
-
brenda
-
-
-
brenda
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
gastrointestinal bacteria
-
-
brenda
-
-
brenda
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
-
-
-
brenda
-
-
-
brenda
Highest Expressing Human Cell Lines
Filter by:
Cell Line Links
Gene Links
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
30000
-
2 * 30000, SDS-PAGE
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
dimer
-
2 * 30000, SDS-PAGE
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Akao, T.; Akao, T.; Hattori, M.; Namba, T.; Kobashi, K.
Purification and properties of 3alpha-hydroxyglycyrrhetinate dehydrogenase of Clostridium innocuum from human intestine
J. Biochem.
103
504-507
1988
[Clostridium] innocuum
brenda
Akao, T.
Localization of enzymes involved in metabolism of glycyrrhizin in contents of rat gastrointestinal tract
Biol. Pharm. Bull.
20
122-126
1997
gastrointestinal bacteria
brenda
Akao, T.
Distribution of enzymes involved in the metabolism of glycyrrhizin in various organs of rat
Biol. Pharm. Bull.
21
1036-1044
1998
Rattus norvegicus
brenda
Akao, T.
Hasty effects on the metabolism of glycyrrhizin by Eubacterium sp. GLH with Ruminococcus sp. PO1-3 and Clstridium innocuum ES24-06 of human intestinal bacteria
Biol. Pharm. Bull.
23
6-11
2000
[Clostridium] innocuum
brenda
html completed
show
top
