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Information on EC 1.1.1.196 - 15-hydroxyprostaglandin-D dehydrogenase (NADP+)

for references in articles please use BRENDA:EC1.1.1.196

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IUBMB Comments

Specific for prostaglandins D [cf. EC 1.1.1.141 15-hydroxyprostaglandin dehydrogenase (NAD+) and EC 1.1.1.197 15-hydroxyprostaglandin dehydrogenase (NADP+)].

The enzyme appears in viruses and cellular organisms

Synonyms
prostaglandin d2 dehydrogenase, nadp+-dependent 15-hydroxyprostaglandin dehydrogenase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(5Z,13E)-(15S)-9alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate + NADP+ = (5Z,13E)-9alpha-hydroxy-11,15-dioxoprosta-5,13-dienoate + NADPH + H+
show the reaction diagram
specific for prostaglandins D cf.EC 1.1.1.141 15-hydroxyprostaglandin dehydrogenase (NAD+) and EC 1.1.1.197 15-hydroxyprostaglandin dehydrogenase (NADP+)
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PATHWAY SOURCE
PATHWAYS
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Highest Expressing Human Cell Lines
Cell Line Links Gene Links