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EC Tree

1 Oxidoreductases

1.1 Acting on the CH-OH group of donors

1.1.1 With NAD⁺ or NADP⁺ as acceptor

1.1.2 With a cytochrome as acceptor

1.1.3 With oxygen as acceptor

1.1.4 With a disulfide as acceptor

1.1.5 With a quinone or similar compound as acceptor

1.1.7 With an iron-sulfur protein as acceptor

1.1.9 With a copper protein as acceptor

1.1.98 With other, known, physiological acceptors

1.1.99 With unknown physiological acceptors

1.2 Acting on the aldehyde or oxo group of donors

1.3 Acting on the CH-CH group of donors

1.4 Acting on the CH-NH₂ group of donors

1.5 Acting on the CH-NH group of donors

1.6 Acting on NADH or NADPH

1.7 Acting on other nitrogenous compounds as donors

1.8 Acting on a sulfur group of donors

1.9 Acting on a heme group of donors

1.10 Acting on diphenols and related substances as donors

1.11 Acting on a peroxide as acceptor

1.12 Acting on hydrogen as donor

1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)

1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

1.15 Acting on superoxide as acceptor

1.16 Oxidizing metal ions

1.17 Acting on CH or CH₂ groups

1.18 Acting on iron-sulfur proteins as donors

1.19 Acting on reduced flavodoxin as donor

1.20 Acting on phosphorus or arsenic in donors

1.21 Catalysing the reaction X-H + Y-H = X-Y

1.22 Acting on halogen in donors

1.23 Reducing C-O-C group as acceptor

1.97 Other oxidoreductases

1.97.1 Sole sub-subclass for oxidoreductases that do not belong in the other subclasses

1.98 Enzymes using H₂ as reductant (deleted subclass)

1.99 Other enzymes using O₂ as oxidant (deleted subclass)

5.1 Racemases and epimerases

5.2 cis-trans-Isomerases

5.3 Intramolecular oxidoreductases

5.4 Intramolecular transferases

5.4.1 Transferring acyl groups

5.4.2 Phosphotransferases (phosphomutases)

5.4.3 Transferring amino groups

5.4.4 Transferring hydroxy groups

5.4.99 Transferring other groups

5.4.99.1 methylaspartate mutase

5.4.99.2 methylmalonyl-CoA mutase

5.4.99.3 2-acetolactate mutase

5.4.99.4 2-methyleneglutarate mutase

5.4.99.5 chorismate mutase

5.4.99.6 created 1972, deleted 2003

5.4.99.7 lanosterol synthase

5.4.99.8 cycloartenol synthase

5.4.99.9 UDP-galactopyranose mutase

5.4.99.10 created 1984, deleted 1992

5.4.99.11 isomaltulose synthase

5.4.99.12 tRNA pseudouridine^38-40 synthase

5.4.99.13 isobutyryl-CoA mutase

5.4.99.14 4-carboxymethyl-4-methylbutenolide mutase

5.4.99.15 (1→4)-α-D-glucan 1-α-D-glucosylmutase

5.4.99.16 maltose α-D-glucosyltransferase

5.4.99.17 squalene—hopene cyclase

5.4.99.18 5-(carboxyamino)imidazole ribonucleotide mutase

5.4.99.19 16S rRNA pseudouridine⁵¹⁶ synthase

5.4.99.20 23S rRNA pseudouridine²⁴⁵⁷ synthase

5.4.99.21 23S rRNA pseudouridine²⁶⁰⁴ synthase

5.4.99.22 23S rRNA pseudouridine²⁶⁰⁵ synthase

5.4.99.23 23S rRNA pseudouridine^{1911/1915/1917} synthase

5.4.99.24 23S rRNA pseudouridine^{955/2504/2580} synthase

5.4.99.25 tRNA pseudouridine⁵⁵ synthase

5.4.99.26 tRNA pseudouridine⁶⁵ synthase

5.4.99.27 tRNA pseudouridine¹³ synthase

5.4.99.28 tRNA pseudouridine³² synthase

5.4.99.29 23S rRNA pseudouridine⁷⁴⁶ synthase

5.4.99.30 UDP-arabinopyranose mutase

5.4.99.31 thalianol synthase

5.4.99.32 protostadienol synthase

5.4.99.33 cucurbitadienol synthase

5.4.99.34 germanicol synthase

5.4.99.35 taraxerol synthase

5.4.99.36 isomultiflorenol synthase

5.4.99.37 dammaradiene synthase

5.4.99.38 camelliol C synthase

5.4.99.39 β-amyrin synthase

5.4.99.40 α-amyrin synthase

5.4.99.41 lupeol synthase

5.4.99.42 tRNA pseudouridine³¹ synthase

5.4.99.43 21S rRNA pseudouridine²⁸¹⁹ synthase

5.4.99.44 mitochondrial tRNA pseudouridine^27/28 synthase

5.4.99.45 tRNA pseudouridine^38/39 synthase

5.4.99.46 shionone synthase

5.4.99.47 parkeol synthase

5.4.99.48 achilleol B synthase

5.4.99.49 glutinol synthase

5.4.99.50 friedelin synthase

5.4.99.51 baccharis oxide synthase

5.4.99.52 α-seco-amyrin synthase

5.4.99.53 marneral synthase

5.4.99.54 β-seco-amyrin synthase

5.4.99.55 δ-amyrin synthase

5.4.99.56 tirucalladienol synthase

5.4.99.57 baruol synthase

5.4.99.58 methylornithine synthase

5.4.99.59 dTDP-fucopyranose mutase

5.4.99.60 cobalt-precorrin-8 methylmutase

5.4.99.61 precorrin-8X methylmutase

5.4.99.62 D-ribose pyranase

5.4.99.63 ethylmalonyl-CoA mutase

5.4.99.64 2-hydroxyisobutanoyl-CoA mutase

5.4.99.65 pre-α-onocerin synthase

5.4.99.66 α-onocerin synthase

5.4.99.67 4-amino-4-deoxychorismate mutase

5.5 Intramolecular lyases

5.6 Isomerases altering macromolecular conformation

5.99 Other isomerases

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Release 2023.1 (January 2023)