EC 188.8.131.52 Details
pyruvate dehydrogenase (quinone)
pyruvate + ubiquinone + H2O = acetate + CO2 + ubiquinol
pyruvate dehydrogenase (ambiguous), pyruvic dehydrogenase (ambiguous), pyruvic (cytochrome b1) dehydrogenase (incorrect), pyruvate:ubiquinone-8-oxidoreductase, pyruvate oxidase (ambiguous), pyruvate dehydrogenase (cytochrome) (incorrect)
Flavoprotein (FAD) . This bacterial enzyme is located on the inner surface of the cytoplasmic membrane and coupled to the respiratory chain via ubiquinone [2,3]. Does not accept menaquinone. Activity is greatly enhanced by lipids [4,5,6]. Requires thiamine diphosphate . The enzyme can also form acetoin .