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EC 1.14.19.10 Details
show Brenda entryEC number
1.14.19.10
Accepted name
icosanoyl-CoA 5-desaturase
Reaction
icosanoyl-CoA + 2 ferrocytochrome b5 + O2 + 2 H+ = (Z)-icos-5-enoyl-CoA + 2 ferricytochrome b5 + 2 H2O
Other name(s)
acyl-CoA Δ5-desaturase (ambiguous)
Systematic name
icosanoyl-CoA,ferrocytochrome b5:oxygen oxidoreductase (5,6 cis-dehydrogenating)
Comment
The enzyme, characterized from the plant Limnanthes douglasii (meadowfoam), is involved in the biosynthesis of (5Z)-icos-5-enoate, an unusual monounsaturated fatty acid that makes up to 60% of the total fatty acids in Limnanthes sp. seed oil. The enzyme only acts on saturated fatty acids.
History
created 2015
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1 Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.4.99.1 D-amino-acid dehydrogenase
