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EC 1.14.13.213 Details
EC number
1.14.13.213
Accepted name
bursehernin 5′-monooxygenase
Reaction
(–)-bursehernin + NADPH + H+ + O2 = (–)-5′-demethylyatein + NADP+ + H2O
Other name(s)
CYP71CU1 (gene name), bursehernin 5′-hydroxylase
Systematic name
(–)-bursehernin,NADPH:oxygen oxidoreductase (5′-hydroxylating)
Comment
This cytochrome P-450 enzyme, characterized from the plant Sinopodophyllum hexandrum, is involved in the biosynthetic pathway of podophyllotoxin, a non-alkaloid toxin lignan whose derivatives are important anticancer drugs.
History
created 2016, deleted 2018
EC Tree
1.14.13.45 created 1992, deleted 2003