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EC 1.14.13.208 Details
show Brenda entryEC number
1.14.13.208
Accepted name
benzoyl-CoA 2,3-epoxidase
Reaction
benzoyl-CoA + NADPH + H+ + O2 = 2,3-epoxy-2,3-dihydrobenzoyl-CoA + NADP+ + H2O
Other name(s)
benzoyl-CoA dioxygenase/reductase (incorrect),
BoxBA,
BoxA/BoxB system,
benzoyl-CoA 2,3-dioxygenase (incorrect)
Systematic name
benzoyl-CoA,NADPH:oxygen oxidoreductase (2,3-epoxydizing)
Comment
The enzyme is involved in aerobic benzoate metabolism in Azoarcus evansii. BoxB functions as the oxygenase part of benzoyl-CoA oxygenase in conjunction with BoxA, the reductase component, which upon binding of benzoyl-CoA, transfers two electrons to the ring in the course of monooxygenation. BoxA is a homodimeric 46 kDa iron-sulfur-flavoprotein (FAD), BoxB is a monomeric iron-protein [1].
History
created 2010 as EC 1.14.12.21, transferred 2015 to EC 1.14.13.208
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1 Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.14.13.45 created 1992, deleted 2003
