Any feedback?
Please rate this page
(ecexplorer.php)
(0/150)

BRENDA support

EC Explorer

EC 1.14.13.205 Details
EC number
1.14.13.205
Accepted name
long-chain fatty acid ω-monooxygenase
Reaction
a long-chain fatty acid + NADPH + H+ + O2 = an ω-hydroxy-long-chain fatty acid + NADP+ + H2O
Other name(s)
CYP704B1 (gene name), CYP52M1 (gene name), CYP4A (gene name), CYP86A (gene name)
Systematic name
long-chain fatty acid,NADPH:oxygen oxidoreductase (ω-hydroxylating)
Comment
The plant enzyme CYP704B1, which is involved in the synthesis of sporopollenin, a complex polymer found at the outer layer of spores and pollen, acts on palmitate (18:0), stearate (18:0) and oleate (18:1). The plant enzyme CYP86A1 also acts on laurate (12:0). The enzyme from the yeast Starmerella bombicola (CYP52M1) acts on C16 to C20 saturated and unsaturated fatty acids and can also hydroxylate the (ω-1) position. The mammalian enzyme CYP4A acts on laurate (12:0), myristate (14:0), palmitate (16:0), oleate (18:1), and arachidonate (20:4).
History
created 2015, deleted 2018
EC Tree
1.14.13.45 created 1992, deleted 2003