EC Explorer
[browse EC tree] - [search]
EC 1.14.13.163 Details
show Brenda entryEC number
1.14.13.163
Accepted name
6-hydroxy-3-succinoylpyridine 3-monooxygenase
Reaction
4-(6-hydroxypyridin-3-yl)-4-oxobutanoate + 2 NADH + 2 H+ + O2 = 2,5-dihydroxypyridine + succinate semialdehyde + 2 NAD+ + H2O
Other name(s)
6-hydroxy-3-succinoylpyridine hydroxylase,
hspA (gene name),
hspB (gene name)
Systematic name
4-(6-hydroxypyridin-3-yl)-4-oxobutanoate,NADH:oxygen oxidoreductase (3-hydroxylating, succinate semialdehyde releasing)
Comment
The enzyme catalyses a reaction in the nicotine degradation pathway of Pseudomonas species. One of the enzymes from the soil bacterium Pseudomonas putida S16 contains an FAD cofactor [2].
History
created 2012
back to topEC Tree
1 Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.14.13.45 created 1992, deleted 2003
