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EC 1.14.13.89 Details
show Brenda entryEC number
1.14.13.89
Accepted name
isoflavone 2′-hydroxylase
Reaction
an isoflavone + NADPH + H+ + O2 = a 2′-hydroxyisoflavone + NADP+ + H2O
Other name(s)
isoflavone 2′-monooxygenase,
CYP81E1,
CYP Ge-3
Systematic name
isoflavone,NADPH:oxygen oxidoreductase (2′-hydroxylating)
CAS registry number
110183-49-8
Comment
A heme-thiolate protein (P-450). Acts on daidzein, formononetin and genistein. EC 1.14.13.53, 4′-methoxyisoflavone 2′-hydroxylase, has the same reaction but is more specific as it requires a 4′-methoxyisoflavone.
History
created 2005, deleted 2018
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1 Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.14.13.45 created 1992, deleted 2003
