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EC 1.14.13.59 Details
show Brenda entryEC number
1.14.13.59
Accepted name
L-lysine N6-monooxygenase (NADPH)
Reaction
L-lysine + NADPH + H+ + O2 = N6-hydroxy-L-lysine + NADP+ + H2O
Other name(s)
lysine N6-hydroxylase,
L-lysine 6-monooxygenase (NADPH) (ambiguous)
Systematic name
L-lysine,NADPH:oxygen oxidoreductase (6-hydroxylating)
CAS registry number
64295-82-5
Comment
A flavoprotein (FAD). The enzyme from strain EN 222 of Escherichia coli is highly specific for L-lysine; L-ornithine and L-homolysine are, for example, not substrates.
History
created 1999, modified 2001, modified 2012
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1 Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.14.13.45 created 1992, deleted 2003
