EC Explorer
[browse EC tree] - [search]
EC 1.14.19.50 Details
show Brenda entryEC number
1.14.19.50
Accepted name
noroxomaritidine synthase
Reaction
(1) 4′-O-methylnorbelladine + [reduced NADPH—hemoprotein reductase] + O2 = (4aR,10bS)-noroxomaritidine + [oxidized NADPH—hemoprotein reductase] + 2 H2O;;(2) 4′-O-methylnorbelladine + [reduced NADPH—hemoprotein reductase] + O2 = (4aS,10bR)-noroxomaritidine + [oxidized NADPH—hemoprotein reductase] + 2 H2O
Other name(s)
CYP96T1 (gene name)
Systematic name
4′-O-methylnorbelladine,NADPH—hemoprotein reductase:oxygen oxidoreductase (noroxomaritidine-forming)
Comment
A P-450 (heme-thiolate) enzyme. The enzyme, characterized from Narcissus pseudonarcissus (daffodil), forms the two enantiomers of the Amaryllidacea alkaloid noroxomaritidine by catalysing intramolecular oxidative para-para′ phenol coupling. The oxidation involves molecular oxygen without its incorporation into the product.
History
created 2016
back to topEC Tree
1 Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.14.19.1 stearoyl-CoA 9-desaturase
