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EC 1.97.1.8 Details
EC number
1.97.1.8
Accepted name
tetrachloroethene reductive dehalogenase
Reaction
trichloroethene + chloride + acceptor = tetrachloroethene + reduced acceptor
Other name(s)
tetrachloroethene reductase
Systematic name
acceptor:trichloroethene oxidoreductase (chlorinating)
CAS registry number
163913-51-7
Comment
This enzyme allows the common pollutant tetrachloroethene to support bacterial growth and is responsible for disposal of a number of chlorinated hydrocarbons by this organism. The reaction occurs in the reverse direction. The enzyme also reduces trichloroethene to dichloroethene. Although the physiological reductant is unknown, the supply of reductant in some organisms is via reduced menaquinone, itself formed from molecular hydrogen, via EC 1.12.5.1 (hydrogen:quinone oxidoreductase). The enzyme contains a corrinoid and two iron-sulfur clusters. Methyl viologen can act as electron donor.
History
created 2001, deleted 2017
EC Tree
1.97.1.5 created 2000 deleted 2001
1.97.1.6 created 2000 deleted 2001
1.97.1.7 created 2000, deleted 2001