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EC 1.3.1.77 Details
EC number
1.3.1.77
Accepted name
anthocyanidin reductase [(2R,3R)-flavan-3-ol-forming]
Reaction
a (2R,3R)-flavan-3-ol + 2 NAD(P)+ = an anthocyanidin with a 3-hydroxy group + 2 NAD(P)H + H+
Other name(s)
ANR (gene name) (ambiguous), flavan-3-ol:NAD(P)+ oxidoreductase, anthocyanidin reductase (ambiguous)
Systematic name
(2R,3R)-flavan-3-ol:NAD(P)+ 3,4-oxidoreductase
CAS registry number
93389-48-1
Comment
The enzyme participates in the flavonoid biosynthesis pathway found in plants. It catalyses the double reduction of anthocyanidins, producing (2R,3R)-flavan-3-ol monomers required for the formation of proanthocyanidins. While the enzyme from the legume Medicago truncatula (MtANR) can use both NADPH and NADH as reductant, that from the crucifer Arabidopsis thaliana (AtANR) uses only NADPH. Also, while the substrate preference of MtANR is cyanidin>pelargonidin>delphinidin, the reverse preference is found with AtANR. cf. EC 1.3.1.112, anthocyanidin reductase [(2S)-flavan-3-ol-forming].
History
created 2004, modified 2016
EC Tree
1.3.1.23 created 1972, deleted 2005
1.3.1.50 created 1992, deleted 1999
1.3.1.55 created 1999, deleted 2004