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EC 1.3.1.74 Details
EC number
1.3.1.74
Accepted name
2-alkenal reductase [NAD(P)+]
Reaction
a n-alkanal + NAD(P)+ = an alk-2-enal + NAD(P)H + H+
Other name(s)
NAD(P)H-dependent alkenal/one oxidoreductase, NADPH:2-alkenal α,β-hydrogenase, 2-alkenal reductase
Systematic name
n-alkanal:NAD(P)+ 2-oxidoreductase
CAS registry number
52227-95-9
Comment
Highly specific for 4-hydroxynon-2-enal and non-2-enal. Alk-2-enals of shorter chain have lower affinities. Exhibits high activities also for alk-2-enones such as but-3-en-2-one and pent-3-en-2-one. Inactive with cyclohex-2-en-1-one and 12-oxophytodienoic acid. Involved in the detoxication of α,β-unsaturated aldehydes and ketones [cf. EC 1.3.1.102, 2-alkenal reductase (NADP+)].
History
created 2003, modified 2014
EC Tree
1.3.1.23 created 1972, deleted 2005
1.3.1.50 created 1992, deleted 1999
1.3.1.55 created 1999, deleted 2004