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EC 1.3.1.93 Details
EC number
1.3.1.93
Accepted name
very-long-chain enoyl-CoA reductase
Reaction
a very-long-chain acyl-CoA + NADP+ = a very-long-chain trans-2,3-dehydroacyl-CoA + NADPH + H+
Other name(s)
TSC13 (gene name), CER10 (gene name)
Systematic name
very-long-chain acyl-CoA:NADP+ oxidoreductase
Comment
This is the fourth component of the elongase, a microsomal protein complex responsible for extending palmitoyl-CoA and stearoyl-CoA (and modified forms thereof) to very-long-chain acyl CoAs. cf. EC 2.3.1.199, very-long-chain 3-oxoacyl-CoA synthase, EC 1.1.1.330, very-long-chain 3-oxoacyl-CoA reductase, and EC 4.2.1.134, very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase.
History
created 2012
EC Tree
1.3.1.23 created 1972, deleted 2005
1.3.1.50 created 1992, deleted 1999
1.3.1.55 created 1999, deleted 2004