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EC Details
EC number
Accepted name
7-chloro-L-tryptophan oxidase
7-chloro-L-tryptophan + O2 = 2-imino-3-(7-chloroindol-3-yl)propanoate + H2O2
Other name(s)
Systematic name
7-chloro-L-tryptophan:oxygen oxidoreductase
Contains a noncovalently bound FAD [1,2]. This enzyme catalyses a step in the biosynthesis of rebeccamycin, an indolocarbazole alkaloid produced by the bacterium Lechevalieria aerocolonigenes. During catalysis, the bound FAD is reoxidized at the expense of molecular oxygen, producing one molecule of hydrogen peroxide. The enzyme shows significant preference for 7-chloro-L-tryptophan over L-tryptophan [1].
created 2010
EC Tree created 1972, deleted 1984 created 2000, deleted 2003 proposed 2000