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EC Details
EC number
Accepted name
diamine oxidase
histamine + H2O + O2 = (imidazol-4-yl)acetaldehyde + NH3 + H2O2
Other name(s)
amine oxidase (ambiguous), amine oxidase (copper-containing) (ambiguous), CAO (ambiguous), Cu-containing amine oxidase (ambiguous), copper amine oxidase (ambiguous), diamine oxidase (ambiguous), diamino oxhydrase (ambiguous), histaminase, histamine deaminase (incorrect), semicarbazide-sensitive amine oxidase (incorrect), SSAO (incorrect)
Systematic name
histamine:oxygen oxidoreductase (deaminating)
A group of enzymes that oxidize diamines, such as histamine, and also some primary monoamines but have little or no activity towards secondary and tertiary amines. They are copper quinoproteins (2,4,5-trihydroxyphenylalanine quinone) and, like EC (primary-amine oxidase) but unlike EC (monoamine oxidase), they are sensitive to inhibition by carbonyl-group reagents, such as semicarbazide.
created 2007 (EC created 1961, part-incorporated 2008)
EC Tree created 1972, deleted 1984 created 2000, deleted 2003 proposed 2000