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EC Details
EC number
Accepted name
primary-amine oxidase
RCH2NH2 + H2O + O2 = RCHO + NH3 + H2O2
Other name(s)
amine oxidase (ambiguous), amine oxidase (copper-containing), amine oxidase (pyridoxal containing) (incorrect), benzylamine oxidase (incorrect), CAO (ambiguous), copper amine oxidase (ambiguous), Cu-amine oxidase (ambiguous), Cu-containing amine oxidase (ambiguous), diamine oxidase (incorrect), diamino oxhydrase (incorrect), histamine deaminase (ambiguous), histamine oxidase (ambiguous), monoamine oxidase (ambiguous), plasma monoamine oxidase (ambiguous), polyamine oxidase (ambiguous), semicarbazide-sensitive amine oxidase (ambiguous), SSAO (ambiguous)
Systematic name
primary-amine:oxygen oxidoreductase (deaminating)
A group of enzymes that oxidize primary monoamines but have little or no activity towards diamines, such as histamine, or towards secondary and tertiary amines. They are copper quinoproteins (2,4,5-trihydroxyphenylalanine quinone) and, unlike EC, monoamine oxidase, are sensitive to inhibition by carbonyl-group reagents, such as semicarbazide. In some mammalian tissues the enzyme also functions as a vascular-adhesion protein (VAP-1).
created 2007 (EC created 1961, part-incorporated 2008)
EC Tree created 1972, deleted 1984 created 2000, deleted 2003 proposed 2000