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EC 1.1.99.38 Details
show Brenda entryEC number
1.1.99.38
Accepted name
2-deoxy-scyllo-inosamine dehydrogenase (AdoMet-dependent)
Reaction
2-deoxy-scyllo-inosamine + S-adenosyl-L-methionine = 3-amino-2,3-dideoxy-scyllo-inosose + 5′-deoxyadenosine + L-methionine
Other name(s)
btrN (gene name),
2-deoxy-scyllo-inosamine dehydrogenase (SAM-dependent)
Systematic name
2-deoxy-scyllo-inosamine:S-adenosyl-L-methionine 1-oxidoreductase
Comment
Involved in the biosynthetic pathway of the aminoglycoside antibiotics of the butirosin family. The enzyme from Bacillus circulans was shown to be a radical S-adenosyl-L-methionine (SAM) enzyme. cf. EC 1.1.1.329, 2-deoxy-scyllo-inosamine dehydrogenase.
History
created 2012, modified 2013
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1 Oxidoreductases
1.1.1 With NAD+ or NADP+ as acceptor
1.1.99.15 created 1978, deleted 1980 1.1.99.17 created 1982, deleted 2003
