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EC 1.1.99.32 Details
show Brenda entryEC number
1.1.99.32
Accepted name
L-sorbose 1-dehydrogenase
Reaction
L-sorbose + acceptor = 1-dehydro-L-sorbose + reduced acceptor
Other name(s)
SDH (ambiguous)
Systematic name
L-sorbose:acceptor 1-oxidoreductase
Comment
The product, L-sorbosone, is an intermediate in bacterial 2-keto-L-gulonic-acid formation. The activity of this membrane-bound enzyme is stimulated by Fe(III) or Co2+ but is inhibited by Cu2+. The enzyme is highly specific for L-sorbose as other sugars, such as glucose, mannitol and sorbitol, are not substrates. Phenazine methosulfate and DCIP can act as artificial acceptors.
History
created 2008
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1 Oxidoreductases
1.1.1 With NAD+ or NADP+ as acceptor
1.1.99.15 created 1978, deleted 1980 1.1.99.17 created 1982, deleted 2003
