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EC Explorer

EC 1.1.1.365 Details
EC number
1.1.1.365
Accepted name
D-galacturonate reductase
Reaction
L-galactonate + NADP+ = D-galacturonate + NADPH + H+
Other name(s)
GalUR, gar1 (gene name)
Systematic name
L-galactonate:NADP+ oxidoreductase
Comment
The enzyme from plants is involved in ascorbic acid (vitamin C) biosynthesis [1,2]. The enzyme from the fungus Trichoderma reesei (Hypocrea jecorina) is involved in a eukaryotic degradation pathway of D-galacturonate. It is also active with D-glucuronate and glyceraldehyde [3]. Neither enzyme shows any activity with NADH.
History
created 2013
EC Tree
1.1.99.15 created 1978, deleted 1980
1.1.99.17 created 1982, deleted 2003