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EC 1.1.1.333 Details
EC number
1.1.1.333
Accepted name
decaprenylphospho-β-D-erythro-pentofuranosid-2-ulose 2-reductase
Reaction
trans,octacis-decaprenylphospho-β-D-arabinofuranose + NAD+ = trans,octacis-decaprenylphospho-β-D-erythro-pentofuranosid-2-ulose + NADH + H+
Other name(s)
decaprenylphospho-β-D-ribofuranose 2′-epimerase,
Rv3791,
DprE2
Systematic name
trans,octacis-decaprenylphospho-β-D-arabinofuranose:NAD+ 2-oxidoreductase
Comment
The reaction is catalysed in the reverse direction. The enzyme, isolated from the bacterium Mycobacterium smegmatis, is involved, along with EC 1.1.98.3, decaprenylphospho-β-D-ribofuranose 2-oxidase, in the epimerization of trans,octacis-decaprenylphospho-β-D-ribofuranose to trans,octacis-decaprenylphospho-β-D-arabinoofuranose, the arabinosyl donor for the biosynthesis of mycobacterial cell wall arabinan polymers.
History
created 2012
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