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EC 5.5.1.22 Details
show Brenda entryEC number
5.5.1.22
Accepted name
(–)-bornyl diphosphate synthase
Reaction
geranyl diphosphate = (–)-bornyl diphosphate
Other name(s)
bornyl pyrophosphate synthase (ambiguous),
bornyl pyrophosphate synthetase (ambiguous),
(–)-bornyl pyrophosphate cyclase,
bornyl diphosphate synthase,
geranyl-diphosphate cyclase (ambiguous),
(–)-bornyl-diphosphate lyase (decyclizing)
Systematic name
(–)-bornyl-diphosphate lyase (ring-opening)
CAS registry number
110639-17-3
Comment
Requires Mg2+. The enzyme from Tanacetum vulgare (tansy) can also use (3S)-linalyl diphosphate or more slowly neryl diphosphate in vitro. The reaction proceeds via isomeration of geranyl diphosphate to (3S)-linalyl diphosphate [3]. The oxygen and phosphorus originally linked to C-1 of geranyl diphosphate end up linked to C-2 of (–)-bornyl diphosphate [4]. cf. EC 5.5.1.8 (+)-bornyl diphosphate synthase.
History
created 2012
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1 Oxidoreductases
1.1.1 With NAD+ or NADP+ as acceptor
1.1.3.1 created 1961, deleted 1984 1.1.3.25 created 1986, deleted 2005 1.1.3.26 created 1989, deleted 2002 1.1.3.31 created 1992, deleted 2003 1.1.3.32 created 1999, deleted 2002 1.1.3.33 created 1999, deleted 2002 1.1.3.34 created 1999, deleted 2002 1.1.3.35 created 1999, deleted 2002 1.1.3.36 created 1999, deleted 2002
