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EC 1.6.5.9 Details
show Brenda entryEC number
1.6.5.9
Accepted name
NADH:quinone reductase (non-electrogenic)
Reaction
NADH + H+ + a quinone = NAD+ + a quinol
Other name(s)
type II NAD(P)H:quinone oxidoreductase,
NDE2 (gene name),
ndh (gene name),
NDH-II,
NDH-2,
NADH dehydrogenase (quinone) (ambiguous),
ubiquinone reductase (ambiguous),
coenzyme Q reductase (ambiguous),
dihydronicotinamide adenine dinucleotide-coenzyme Q reductase (ambiguous),
DPNH-coenzyme Q reductase (ambiguous),
DPNH-ubiquinone reductase (ambiguous),
NADH-coenzyme Q oxidoreductase (ambiguous),
NADH-coenzyme Q reductase (ambiguous),
NADH-CoQ oxidoreductase (ambiguous),
NADH-CoQ reductase (ambiguous),
NADH-ubiquinone reductase (ambiguous),
NADH-ubiquinone oxidoreductase (ambiguous),
reduced nicotinamide adenine dinucleotide-coenzyme Q reductase (ambiguous),
NADH-Q6 oxidoreductase (ambiguous),
NADH2 dehydrogenase (ubiquinone) (ambiguous),
NADH:ubiquinone oxidoreductase,
NADH:ubiquinone reductase (non-electrogenic)
Systematic name
NADH:quinone oxidoreductase
CAS registry number
9028-04-0
Comment
A flavoprotein (FAD or FMN). Occurs in mitochondria of yeast and plants, and in aerobic bacteria. Has low activity with NADPH. Unlike EC 7.1.1.2, NADH:ubiquinone reductase (H+-translocating), this enzyme does not pump proteons of sodium ions across the membrane. It is also not sensitive to rotenone.
History
created 2011 (EC 1.6.5.11 created 1972 as EC 1.6.99.5, transferred 2015 to EC 1.6.5.11, incorporated 2019), modified 2019
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1 Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.6.5.1 created 1961, deleted 1965
