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EC Details
EC number
Accepted name
3-oxo-5,6-dehydrosuberyl-CoA semialdehyde dehydrogenase
3-oxo-5,6-dehydrosuberyl-CoA semialdehyde + NADP+ + H2O = 3-oxo-5,6-dehydrosuberyl-CoA + NADPH + H+
Other name(s)
paaZ (gene name)
Systematic name
3-oxo-5,6-dehydrosuberyl-CoA semialdehyde:NADP+ oxidoreductase
The enzyme from Escherichia coli is a bifunctional fusion protein that also catalyses EC, oxepin-CoA hydrolase.Combined the two activities result in a two-step conversion of oxepin-CoA to 3-oxo-5,6-dehydrosuberyl-CoA, part of an aerobic phenylacetate degradation pathway.
created 2011, deleted 2014
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