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EC 1.14.13.152 Details
EC number
1.14.13.152
Accepted name
geraniol 8-hydroxylase
Reaction
geraniol + NADPH + H+ + O2 = (6E)-8-hydroxygeraniol + NADP+ + H2O
Other name(s)
CYP76B6, G10H, CrG10H, SmG10H
Systematic name
geraniol,NADPH:oxygen oxidoreductase (8-hydroxylating)
Comment
Requires cytochrome P-450. Also hydroxylates nerol and citronellol, cf. EC 1.14.13.151 linalool 8-monooxygenase. The recommended numbering of geraniol gives 8-hydroxygeraniol as the product rather than 10-hydroxygeraniol as used by references 1-3. See prenol nomenclature Pr-1. The cloned enzyme also catalysed, but less efficiently, the 3′-hydroxylation of naringenin (cf. EC 1.14.13.21, flavonoid 3′-monooxygenase) [3].
History
created 2012, deleted 2018
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