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EC 1.16.1.7 Details
EC number
1.16.1.7
Accepted name
ferric-chelate reductase (NADH)
Reaction
2 Fe(II)-siderophore + NAD+ + H+ = 2 Fe(III)-siderophore + NADH
Other name(s)
ferric chelate reductase (ambiguous), iron chelate reductase (ambiguous), NADH:Fe3+-EDTA reductase, NADH2:Fe3+ oxidoreductase, ferB (gene name), Fe(II):NAD+ oxidoreductase
Systematic name
Fe(II)-siderophore:NAD+ oxidoreductase
CAS registry number
120720-17-4
Comment
Contains FAD. The enzyme catalyses the reduction of bound ferric iron in a variety of iron chelators (siderophores), resulting in the release of ferrous iron. The plant enzyme is involved in the transport of iron across plant plasma membranes. The enzyme from the bacterium Paracoccus denitrificans can also reduce chromate. cf. EC 1.16.1.9, ferric-chelate reductase (NADPH) and EC 1.16.1.10, ferric-chelate reductase [NAD(P)H].
History
created 1992 as EC 1.6.99.13, transferred 2002 to EC 1.16.1.7, modified 2011, modified 2014
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