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1.3.1.91: tRNA-dihydrouridine20 synthase [NAD(P)+]

This is an abbreviated version!
For detailed information about tRNA-dihydrouridine20 synthase [NAD(P)+], go to the full flat file.

Wordmap for 1.3.1.91

Word Map on EC 1.3.1.91 Wordmap for 1.3.1.91

Reaction

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5,6-dihydrouracil20 in tRNA
+
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NAD(P)+
=
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uracil20 in tRNA
+
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NAD(P)H
+
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H+

Synonyms

dihydrouridine synthase, dihydrouridine synthase 2, dihydrouridine synthase C, Dus, DUS 2, DUS2, Dus2p, DusA, DusB, DusC, EcoDusC, hDUS2, HsDus2, SMM1, tRNA-dihydrouridine synthase 2, tRNA-dihydrouridine synthases

ECTree

     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.1 With NAD+ or NADP+ as acceptor
                EC 1.3.1.911.3.1.91 tRNA-dihydrouridine20 synthase [NAD(P)+]

Substrates Products

Substrates Products on EC 1.3.1.91 - tRNA-dihydrouridine20 synthase [NAD(P)+]

for references in articles please use BRENDA:EC1.3.1.91

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SUBSTRATE
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
LITERATURE
COMMENTARY hide
Reversibility
r=reversible
ir=irreversible
?=not specified
more the enzyme it is not able to synthetize uracil16 in tRNA
?
show the reaction diagram
uracil in bulk tRNA + NADH + H+
5,6-dihydrouracil in bulk tRNA + NAD+
show the reaction diagram
uracil in bulk tRNA + NADPH + H+
5,6-dihydrouracil in bulk tRNA + NADP+
show the reaction diagram
Substrates: the enzyme exhibits a clear preference for NADPH compared to NADH
Products: -
?
uracil in pre-tRNALeu + NAD(P)H + H+
5,6-dihydrouracil in pre-tRNALeu + NAD(P)+
show the reaction diagram
Substrates: -
Products: -
?
uracil in pre-tRNATyr + NAD(P)H + H+
5,6-dihydrouracil in pre-tRNATyr + NAD(P)+
show the reaction diagram
Substrates: -
Products: -
?
uracil in tRNA + NAD(P)H + H+
5,6-dihydrouracil in tRNA + NAD(P)+
show the reaction diagram
uracil17 in tRNA + NADPH + H+
5,6-dihydrouracil17 in tRNA + NADP+
show the reaction diagram
uracil20 in tRNA + NAD(P)H + H+
5,6-dihydrouracil20 in tRNA + NAD(P)+
show the reaction diagram
uracil20 in tRNA + NADH + H+
5,6-dihydrouracil20 in tRNA + NAD+
show the reaction diagram
Substrates: -
Products: -
?
uracil20 in tRNA + NADPH + H+
5,6-dihydrouracil20 in tRNA + NADP+
show the reaction diagram
uracil20a in tRNA + NADH + H+
5,6-dihydrouracil20a in tRNA + NAD+
show the reaction diagram
Substrates: -
Products: -
?
uracil20a in tRNA + NADPH + H+
5,6-dihydrouracil20a in tRNA + NADP+
show the reaction diagram
additional information
?
-