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EC 1.1.1.411: L-threonate 2-dehydrogenase

This is an abbreviated version!
For detailed information about L-threonate 2-dehydrogenase, go to the full flat file.

Reaction

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L-threonate
+
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NAD+
=
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2-dehydro-L-erythronate
+
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NADH
+
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H+

Synonyms

L-threonate dehydrogenase, L-threonic acid dehydrogenase, ltnD, ThrDH

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                EC 1.1.1.4111.1.1.411 L-threonate 2-dehydrogenase

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Resultsin table
2429AA Sequence
8Cofactor
10kcat/KM [mM/s]
10KM Value [mM]
2Natural Substrates/ Products (Substrates)
12Organism
1Pathway
4Purification (Commentary)
1Reaction
12Reference
26Substrates and Products (Substrate)
23Synonyms
1Systematic Name
10Turnover Number [1/s]
All data fields related to EC 1.1.1.411

Reference

Reference on EC 1.1.1.411 - L-threonate 2-dehydrogenase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Zhang, X.; Carter, M.; Vetting, M.; Francisco, B.; Zhao, S.; Al-Obaidi, N.; Solbiati, J.; Thiaville, J.; Crecy-Lagard, V.; Jacobson, M.; Almo, S.; Gerlt, J.
Assignment of function to a domain of unknown function: DUF1537 is a new kinase family in catabolic pathways for acid sugars
Proc. Natl. Acad. Sci. USA
113
E4161-E4169
2016
Cupriavidus necator (Q0KBC7), Cupriavidus necator DSM 428 (Q0KBC7), Pectobacterium atrosepticum (Q6CZ26), Pectobacterium atrosepticum ATCC BAA-672 (Q6CZ26)
Manually annotated by BRENDA team
Zhang, C.F.; Liu, Y.P.; Wu, X.X.; Zhang, X.S.; Huang, H.
Substrate diversity of L-threonic acid dehydrogenase homologs
Biochemistry (Moscow)
85
463-471
2020
Agrobacterium tumefaciens (B9JKN9), Agrobacterium tumefaciens (B9J8U1), Agrobacterium tumefaciens ATCC BAA-868 (B9JKN9), Agrobacterium tumefaciens ATCC BAA-868 (B9J8U1), Chromohalobacter israelensis (Q1QSN6), Chromohalobacter israelensis ATCC BAA-138 (Q1QSN6), Cupriavidus necator (Q0KBC7), Cupriavidus necator ATCC 17699 (Q0KBC7)
Manually annotated by BRENDA team