1.1.1.361: glucose-6-phosphate 3-dehydrogenase
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For detailed information about glucose-6-phosphate 3-dehydrogenase, go to the full flat file.
Reaction
Synonyms
G6P 3-dehydrogenase, ntdC, yhjJ
ECTree
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Reaction
Reaction on EC 1.1.1.361 - glucose-6-phosphate 3-dehydrogenase
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D-glucose 6-phosphate + NAD+ = 3-dehydro-D-glucose 6-phosphate + NADH + H+
NtdC follows a random sequential mechanism, consistent with our product inhibition. The equilibrium position of the NtdC-catalyzed reaction greatly favors G6P, and the rate of 3-dehydro-D-glucose 6-phosphate formation at neutral pH is very low, under more favorable basic conditions, the product of the reaction is unstable
D-glucose 6-phosphate + NAD+ = 3-dehydro-D-glucose 6-phosphate + NADH + H+
NtdC follows a random sequential mechanism, consistent with our product inhibition. The equilibrium position of the NtdC-catalyzed reaction greatly favors G6P, and the rate of 3-dehydro-D-glucose 6-phosphate formation at neutral pH is very low, under more favorable basic conditions, the product of the reaction is unstable
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