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1.1.1.299: malate dehydrogenase [NAD(P)+]

This is an abbreviated version!
For detailed information about malate dehydrogenase [NAD(P)+], go to the full flat file.

Word Map on EC 1.1.1.299

Reaction

(S)-malate
+
NAD(P)+
=
oxaloacetate
+
NAD(P)H
+
H+

Synonyms

LDH-like MalDH, MDH II, NAD(P)-dependent malate dehydrogenase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.299 malate dehydrogenase [NAD(P)+]

Inhibitors

Inhibitors on EC 1.1.1.299 - malate dehydrogenase [NAD(P)+]

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
CuCl2
-
1 mM, 10% residual activity
HgCl2
-
1 mM, no residual activity
iodoacetate
-
1 mM, 16.4% residual activity
N-ethylmaleimide
-
1 mM, no residual activity
NADH
-
inhibitory above 0.2 mM
NADPH
-
inhibitory above 0.2 mM
oxaloacetate
-
-
ZnCl2
-
1 mM, 27% residual activity