EC 1.1.1.255: mannitol dehydrogenase

This is an abbreviated version!
For detailed information about mannitol dehydrogenase, go to the full flat file.

Reaction

Synonyms

mannitol 1-dehydrogenase, mannitol 1-oxidoreductase, mannitol:mannose 1-oxidoreductase, MTD, NAD-dependent mannitol dehydrogenase

ECTree

     1 Oxidoreductases

         1.1 Acting on the CH-OH group of donors

             1.1.1 With NAD⁺ or NADP⁺ as acceptor

                1.1.1.255 mannitol dehydrogenase

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All data fields related to EC 1.1.1.255

Results	in table
1	Activating Compound
530	AA Sequence
2	Application
1	CAS Registry Number
3	Cloned(Commentary)
7	Cofactor
1	General Information
12	Inhibitors
8	KM Value [mM]
3	Localization
4	Molecular Weight [Da]
14	Natural Substrates/ Products (Substrates)
15	Organism
1	Pathway
3	pH Range
2	Purification (Commentary)
1	Reaction
3	Reaction Type
15	Reference
20	Source Tissue
5	Specific Activity [micromol/min/mg]
2	Storage Stability
21	Substrates and Products (Substrate)
1	Subunits
9	Synonyms
1	Systematic Name

Substrates Products

Substrates Products on EC 1.1.1.255 - mannitol dehydrogenase

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SUBSTRATE

PRODUCT

REACTION DIAGRAM

ORGANISM

UNIPROT

LITERATURE

COMMENTARY

Reversibility
r=reversible
ir=irreversible
?=not specified

D-arabinitol + NAD+

D-lyxose + NADH + H+

Apium graveolens

-

286399

Substrates: -
Products: -

r

D-glucitol + NAD+

D-gulose + NADH

2 entries

D-iditol + NAD+

D-idose + NADH

Apium graveolens

-

286399

Substrates: -
Products: -

r

D-mannitol + NAD+

D-mannose + NADH + H+

4 entries

D-talose + NADH

D-altritol + NAD+

Apium graveolens

-

286399

Substrates: -
Products: -

ir

D-threitol + NAD+

D-threose + NADH

Apium graveolens

-

286399

Substrates: 25% activity
Products: -

r

galactitol + NAD+

galactose + NADH

Apium graveolens

-

286403

Substrates: low activity
Products: -

r

i-erythreitol + NAD+

? + NADH

Apium graveolens

-

286399

Substrates: 16% activity
Products: -

?

i-galactitol + NAD+

L-galactose + NADH

Apium graveolens

-

286399

Substrates: not oxidized by higher plants
Products: -

r

i-ribitol + NAD+

L-ribose + NADH

Apium graveolens

-

286399

Substrates: -
Products: -

r

L-arabinitol + NAD+

L-arabinose + NADH

Apium graveolens

-

286399

Substrates: -
Products: -

r

L-iditol + NAD+

L-idose + NADH

Apium graveolens

-

286399

Substrates: less than 10% activity
Products: -

r

additional information

?

-

Apium graveolens

-

286404

Substrates: no cinnamyl alcohol dehydrogenase activity
Products: -

?

D-glucitol + NAD+

D-gulose + NADH

Apium graveolens

-

286403

Substrates: low activity
Products: -

r

D-glucitol + NAD+

D-gulose + NADH

Apium graveolens

-

286399

Substrates: not oxidized by higher plants
Products: -

r

D-mannitol + NAD+

D-mannose + NADH + H+

Apium graveolens

-

286400, 286402, 286403, 286404

Substrates: -
Products: -

r

D-mannitol + NAD+

D-mannose + NADH + H+

Apium graveolens

-

286399

Substrates: highest activity, aldoses having 2S chirality are not reducible, with the exception of D-idose, marked preference for aldopentose and aldohexose, same stereospecificity in either direction with the same absolute configuration at C-2
Products: -

r

D-mannitol + NAD+

D-mannose + NADH + H+

Apium graveolens

-

286401

Substrates: mannitol pool size is important for regulating salt tolerance
Products: -

r

D-mannitol + NAD+

D-mannose + NADH + H+

Apium graveolens

Q38707

700868, 741145

Substrates: -
Products: -

?