Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

EC 1.1.1.255: mannitol dehydrogenase

This is an abbreviated version!
For detailed information about mannitol dehydrogenase, go to the full flat file.

Wordmap for 1.1.1.255

Word Map on EC 1.1.1.255 Wordmap for 1.1.1.255

Reaction

Show molfile
D-mannitol
+
Show molfile
NAD+
=
Show molfile
D-mannose
 +
Show molfile
NADH
 +
Show molfile
H+

Synonyms

mannitol 1-dehydrogenase, mannitol 1-oxidoreductase, mannitol:mannose 1-oxidoreductase, MTD, NAD-dependent mannitol dehydrogenase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                EC 1.1.1.2551.1.1.255 mannitol dehydrogenase

Inhibitors

Inhibitors on EC 1.1.1.255 - mannitol dehydrogenase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
1,10-phenanthroline
-
dose dependent decrease in enzyme activity
1,4-dithioerythritol
-
1.09 mM, 50% inhibition, partially reversed by diamide
1,4-dithiothreitol
-
0.57 mM, 50% inhibition, reversed by diamide
2-mercaptoethanol
-
30 mM, 50% inhibition, partially reversed by diamide
AMP
-
Ki: 0.50-0.80 mM at pH 9.5, Ki = 0.64 mM at pH 7.0
ATP
-
Ki: 1.10 mM at pH 7.0
D-mannose
-
competitive inhibition, Ki: 200 mM
D-threose
-
competitive inhibition, Ki: 18 mM
NADH
-
strong inhibition at 0.1 mM
additional information
-
EDTA and EGTA did not affect enzyme activity
-