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1.1.1.21: aldose reductase

This is an abbreviated version!
For detailed information about aldose reductase, go to the full flat file.

Word Map on EC 1.1.1.21

Reaction

alditol
+
NAD(P)+
=
aldose
+
NAD(P)H
+
H+

Synonyms

17betaHSD5, 20-alpha-HSD, 20-alpha-hydroxysteroid dehydrogenase, AdhA, AKR1B, AKR1B1, AKR1B10, AKR1B13, AKR1B14, AKR1B3, AKR1C3, AKR4C7, aldehyde reductase, alditol/NADP+ oxidoreductase, alditol: NADP+ 1-oxidoreductase, alditol:NAD(P)+1oxidoreductase, alditol:NADP 1-oxidoreductase, alditol:NADP oxidoreductase, aldo-keto reductase, aldo-keto reductase family 1 member B1, aldo-keto reductase family 1 member B7, aldoketo reductase 1C3, aldose reductase, aldose reductase 2, aldose reductase-like, aldose reductase-like protein, aldose xylose reductase, ALDRXV4, ALR, ALR1, ALR2, AR, ARI, BAR, EC 1.1.1.139, Fibroblast growth factor regulated protein, FR-1 protein, GRE3, HAR, HRAR, isobutyraldehyde reductase, More, MVDP, NADPH dependent xylose reductase, NADPH-aldopentose reductase, NADPH-aldose reductase, polyol dehydrogenase (NADP2), RLAR, small intestine reductase, TPN-polyol dehydrogenase, VAS deferens androgen-dependent protein, YqhD

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.21 aldose reductase

KCat KM Value

KCat KM Value on EC 1.1.1.21 - aldose reductase

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kcat/KM VALUE [1/mMs-1]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
24
3-Nitrobenzaldehyde
pH 7.0, 45°C
3.3
benzaldehyde
pH 7.0, 45°C
1.5
D-arabinose
pH 7.0, 45°C
0.2
D-galactose
pH 7.0, 45°C
0.24
D-ribose
pH 7.0, 45°C
1
D-xylose
pH 7.0, 45°C
5.3
DL-glyceraldehyde
pH 6.2, temperature not specified in the publication, recombinant His-tagged enzyme
0.58
Glyoxal
pH 7.0, 45°C
12
isophthalaldehyde
pH 7.0, 45°C
9.3
methylglyoxal
pH 6.2, temperature not specified in the publication, recombinant His-tagged enzyme
728
NADPH
pH 7.0, 45°C
1.6
Pyridine-3-aldehyde
pH 7.0, 45°C