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EC 1.1.1.209: 3(or 17)alpha-hydroxysteroid dehydrogenase

This is an abbreviated version!
For detailed information about 3(or 17)alpha-hydroxysteroid dehydrogenase, go to the full flat file.

Wordmap for 1.1.1.209

Word Map on EC 1.1.1.209 Wordmap for 1.1.1.209

Reaction

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androsterone
+
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NAD(P)+
=
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5alpha-androstane-3,17-dione
+
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NAD(P)H
+
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H+

Synonyms

3(17)alpha-hydroxysteroid dehydrogenase, 3beta- and 17beta-hydroxysteroid dehydrogenase, AKR1C21, dehydrogenase, 3(17)alpha-hydroxy steroid, More

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                EC 1.1.1.2091.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase

Natural Substrates Products

Natural Substrates Products on EC 1.1.1.209 - 3(or 17)alpha-hydroxysteroid dehydrogenase

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
LITERATURE
COMMENTARY hide
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
21-hydroxy-5beta-pregnane-3,20-dione + NADPH
21-hydroxy-5beta-pregnane-20alpha-ol-3-one + NADP+
show the reaction diagram
Substrates: -
Products: -
r
5beta-pregnane-3alpha,20alpha-diol + NADPH + H+
5beta-pregnane-20alpha-ol-3-one + NADP+
show the reaction diagram
Substrates: -
Products: -
r
androstenedione + NADPH + H+
androsterone + NADP+
show the reaction diagram
Substrates: -
Products: -
r
additional information
?
-
-
Substrates: the enzyme catalyses the oxidoreduction of steroid hormones such as estrogens, androgens and neurosteroids
Products: -
?