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1.1.1.193: 5-amino-6-(5-phosphoribosylamino)uracil reductase

This is an abbreviated version!
For detailed information about 5-amino-6-(5-phosphoribosylamino)uracil reductase, go to the full flat file.

Reaction

5-amino-6-(5-phospho-D-ribitylamino)uracil
+
NADP+
=
5-amino-6-(5-phospho-D-ribosylamino)uracil
+
NADPH
+
H+

Synonyms

aminodioxyphosphoribosylaminopyrimidine reductase, HTP reductase, Rib7, RibD, RibG, riboflavin biosynthesis protein

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.193 5-amino-6-(5-phosphoribosylamino)uracil reductase

Reference

Reference on EC 1.1.1.193 - 5-amino-6-(5-phosphoribosylamino)uracil reductase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Richter, G.; Fischer, M.; Krieger, C.; Eberhardt, S.; Luttgen, H.; Gerstenschläger, I.; Bacher, A.
Biosynthesis of riboflavin: characterization of the bifunctional deaminase-reductase of Escherichia coli and Bacillus subtilis
J. Bacteriol.
179
2022-2028
1997
Bacillus subtilis (P17618), Escherichia coli (P25539)
Manually annotated by BRENDA team
Burrows, R.B.; Brown, G.M.
Presence in Escherichia coli of a deaminase and a reductase involved in biosynthesis of riboflavin
J. Bacteriol.
136
657-667
1978
Escherichia coli, Escherichia coli B / ATCC 11303
Manually annotated by BRENDA team
Grill, S.; Yamaguchi, H.; Wagner, H.; Zwahlen, L.; Kusch, U.; Mack, M.
Identification and characterization of two Streptomyces davawensis riboflavin biosynthesis gene clusters
Arch. Microbiol.
188
377-387
2007
Streptomyces davaonensis (Q2VCF5), Streptomyces davaonensis, Streptomyces davaonensis 768 (Q2VCF5)
Manually annotated by BRENDA team
Dawson, A.; Trumper, P.; Chrysostomou, G.; Hunter, W.N.
Structure of diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase from Acinetobacter baumannii
Acta Crystallogr. Sect. F
69
611-617
2013
Acinetobacter baumannii (D0CB74)
Manually annotated by BRENDA team
Chen, S.; Yen, T.; Chang, T.; Liaw, S.
Evolution of archaeal Rib7 and eubacterial RibG reductases in riboflavin biosynthesis Substrate specificity and cofactor preference
Biochem. Biophys. Res. Commun.
503
195-201
2018
Bacillus subtilis, Methanosarcina mazei
Manually annotated by BRENDA team