EC 1.1.1.170: 3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating)

This is an abbreviated version!
For detailed information about 3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating), go to the full flat file.

Word Map on EC 1.1.1.170

1.1.1.170

child

x-linked

dehydrogenase-like

hemidysplasia

ichthyosiform

nevus

erythroderma

erg27p

ebp

verruciform

dhcr24

xanthoma

male-lethal

cyp51a1

verrucous

Reaction

Show molfile — a 3beta-hydroxysteroid-4alpha-carboxylate

Synonyms

3beta-hydroxy-4alpha-methylcholestenecarboxylate 3-dehydrogenase (decarboxylating), 3beta-hydroxy-4beta-methylcholestenoate dehydrogenase, 4alpha-carboxylic acid decarboxylase, C-3 sterol dehydrogenase(C-4 decarboxylase), Erg26, Erg26p, NSDHL, sterol 4alpha-carboxylic decarboxylase, sterol-4-alpha-carboxylate 3-dehydrogenase, sterol-4-alpha-carboxylate-3-dehydrogenase, sterol-4alpha-carboxylate 3-dehydrogenase

ECTree

1 Oxidoreductases

1.1 Acting on the CH-OH group of donors

1.1.1 With NAD⁺ or NADP⁺ as acceptor

1.1.1.170 3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating)

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All data fields related to EC 1.1.1.170
Results	in table
740	AA Sequence
1	CAS Registry Number
2	Cloned(Commentary)
4	Cofactor
95	Disease/ Diagnostics
14	General Information
4	IC50 Value
7	Inhibitors
1	Ki Value [mM]
4	KM Value [mM]
2	Localization
8	Natural Substrates/ Products (Substrates)
9	Organism
8	Pathway
4	PDB ID
3	pH Optimum
1	pH Range
1	Posttranslational Modification
7	Protein Variants
1	Purification (Commentary)
1	Reaction
3	Reaction Type
9	Reference
2	Source Tissue
1	Specific Activity [micromol/min/mg]
1	Storage Stability
15	Substrates and Products (Substrate)
2	Subunits
21	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]

Natural Substrates Products

Natural Substrates Products on EC 1.1.1.170 - 3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating)

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3beta-hydroxy-4alpha-methyl-5alpha-cholest-7-ene-4beta-carboxylate + NAD+

4alpha-methyl-5alpha-cholest-7-en-3-one + CO2 + NADH

Rattus sp.

286111

Substrates: -
Products: -

3beta-hydroxy-4beta-methyl-5alpha-cholest-7-en-4alpha-oic acid + NAD+

4alpha-methyl-5alpha-cholest-7-en-3-one + CO2 + NADH

Rattus sp.

286111

Substrates: no epimerization of 4beta-isomer into 4alpha-isomer
Products: -

a 3beta-hydroxysteroid-4alpha-carboxylate + NAD(P)+

a 3-oxosteroid + CO2 + NAD(P)H

5 entries

additional information

Mus musculus

656813

Substrates: involved in the removal of C-4 methyl groups in postsqualene cholesterol synthesis
Products: -