Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

1.1.1.159: 7alpha-hydroxysteroid dehydrogenase

This is an abbreviated version!
For detailed information about 7alpha-hydroxysteroid dehydrogenase, go to the full flat file.

Word Map on EC 1.1.1.159

Reaction

cholate
+
NAD+
=
3alpha,12alpha-dihydroxy-7-oxo-5beta-cholan-24-oate
+
NADH
+
H+

Synonyms

7-alpha-HSDH, 7-HSDH, 7alpha-HSD, 7alpha-HSDH, 7alpha-hydroxy steroid dehydrogenase, 7alpha-hydroxysteroid dehydrogenase, Bile acid-inducible protein, CA 7alpha-HSDH, Ca7alpha-HSDH, dehydrogenase, 7alpha-hydroxy steroid, J-1-1, NADP(H)-dependent 7alpha-HSDH, NADP(H)-dependent 7alpha-hydroxysteroid dehydrogenase, NADP+-dependent 7alpha-HSDH, nicotinamide adenine dinucleotide phosphate-dependent 7alpha-hydroxysteroid dehydrogenase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.159 7alpha-hydroxysteroid dehydrogenase

Natural Substrates Products

Natural Substrates Products on EC 1.1.1.159 - 7alpha-hydroxysteroid dehydrogenase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
7-keto-lithocholic acid + NADH
cheno-deoxycholic acid + NAD+
show the reaction diagram
-
in the gastrointestinal tract of host organisms
-
-
?
bile acids + NAD(P)+
?
show the reaction diagram
cholate + NAD+
3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanate + NADH + H+
show the reaction diagram
taurochenodeoxycholic acid + NADP+
tauro-7-ketolithocholic acid + NADPH + H+
show the reaction diagram
-
-
-
?
additional information
?
-