1.1.1.101: acylglycerone-phosphate reductase

This is an abbreviated version!
For detailed information about acylglycerone-phosphate reductase, go to the full flat file.

Reaction

Synonyms

1-acylglycerol-3-phosphate:NADP+ oxidoreductase, acyl/alkyl dihydroxyacetone-phosphate reductase, acyldihydroxyacetone phosphate reductase, acyldihydroxyacetone-phosphate oxidoreductase, acyldihydroxyacetone-phosphate:NADPH oxidoreductase, palmitoyl dihydroxyacetone phosphate reductase, palmitoyl-dihydroxyacetone-phosphate reductase, palmitoyldihydroxyacetone-phosphate reductase, reductase, palmitoyl dihydroxyacetone phosphate

ECTree

     1 Oxidoreductases

         1.1 Acting on the CH-OH group of donors

             1.1.1 With NAD⁺ or NADP⁺ as acceptor

                1.1.1.101 acylglycerone-phosphate reductase

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Results	in table
11	Activating Compound
21	AA Sequence
1	CAS Registry Number
1	Cloned(Commentary)
27	Cofactor
4	Disease/ Diagnostics
17	General Stability
22	Inhibitors
29	KM Value [mM]
5	Molecular Weight [Da]
29	Natural Substrates/ Products (Substrates)
1	Organic Solvent Stability
184	Organism
5	Pathway
5	pH Optimum
1	pH Range
3	Purification (Commentary)
1	Reaction
2	Reaction Type
19	Reference
23	Source Tissue
8	Specific Activity [micromol/min/mg]
3	Storage Stability
93	Substrates and Products (Substrate)
3	Subunits
9	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
1	Temperature Range [°C]
7	Temperature Stability [°C]
1	Turnover Number [1/s]

Inhibitors

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Inhibitors on EC 1.1.1.101 - acylglycerone-phosphate reductase

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INHIBITOR

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

alkyldihydroxyacetone phosphate

Cavia porcellus

-

at high concentrations

285688

chymotrypsin

Rattus norvegicus

-

inactivation

285686

-

divalent cations

Saccharomyces cerevisiae

-

i.e. Cu2+, Co2+, Ca2+, Mg2+, Mn2+, Ni2+, Zn2+, strong inhibition

285691

-

EDTA

Saccharomyces cerevisiae

-

weak inhibition

285691

F-

Saccharomyces cerevisiae

-

weak inhibition

285691

N-ethylmaleimide

2 entries

NADP+

2 entries

palmitoyl-CoA

2 entries

Palmitoyldihydroxyacetone phosphate

Cavia porcellus

-

competitive to hexadecyldihydroxyacetone phosphate

285690

PCMB

Cavia porcellus

-

-

285690

phosphatidylcholine

Cavia porcellus

-

at high concentrations

285690

phosphatidylethanolamine

Cavia porcellus

-

-

285690

phosphatidylglycerol

Cavia porcellus

-

at high concentrations

285690

phosphatidylinositol

Cavia porcellus

-

-

285690

Trypsin

2 entries

-

additional information

2 entries

-

N-ethylmaleimide

Cavia porcellus

-

not inhibitory

285690

N-ethylmaleimide

Saccharomyces cerevisiae

-

strong inhibitor

285691

NADP+

Cavia porcellus

-

competitive to NADPH

285688

NADP+

Cavia porcellus

-

-

285690

palmitoyl-CoA

Cavia porcellus

-

-

285688

palmitoyl-CoA

Cavia porcellus

-

competitive to NADPH, not to alkyldihydroxyacetone phosphate

285690

Trypsin

Cavia porcellus

-

inactivation

285688

-

Trypsin

Rattus norvegicus

-

inactivation

285686, 285688

-

additional information

Cavia porcellus

-

DTNB and thiols; stable to N-ethylmaleimide

285688

-

additional information

Cavia porcellus

-

stable to N-ethylmaleimide

285690

-